Dergiler / Turkish Journal of Hematology / 2018 / Cilt: 35 - Sayı: 3

Anemia and Its Effect on Cardiovascular Findings in Obese Adolescents

Obez Ergenlerde Anemi ve Aneminin Kardiyovasküler Bulgulara Etkisi

Sayfa
192–196
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Even mild anemia may causeincreased heart rate and affect left ventricular diastolic functions.Diet programs for obese children should be carefully planned to avoidiron deficiency anemia, which may worsen the cardiac events in longterm follow-up.

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Amaç & Hipotez:Objective: We assessed the effect of anemia on cardiovascularfindings in obese adolescents.Materials and Methods: We studied 29 anemic and 33 nonanemicobese adolescents, and 33 nonobese healthy adolescents.
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Temel Bulgular & Veri:Echocardiography was used to examine cardiacfunctions.Results: The anemia was mild (mean hemoglobin: 11.67±0.79g/dL), ferritin level was significantly low, and C-reactive protein andfibrinogen levels were significantly high in anemic obese patients.Increased cardiac pulse and echocardiographic findings, which may beindicative of early left ventricular diastolic dysfunction, were presentin these patients.Conclusion: Anemia may develop due to iron deficiency and chronicinflammation in obese adolescents.
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Sonuç & Katkı:Even mild anemia may causeincreased heart rate and affect left ventricular diastolic functions.Diet programs for obese children should be carefully planned to avoidiron deficiency anemia, which may worsen the cardiac events in longterm follow-up.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: We assessed the effect of anemia on cardiovascularfindings in obese adolescents.Materials and Methods: We studied 29 anemic and 33 nonanemicobese adolescents, and 33 nonobese healthy adolescents. These threegroups were investigated for clinical and laboratory features ofanemia and obesity. Echocardiography was used to examine cardiacfunctions.Results: The anemia was mild (mean hemoglobin: 11.67±0.79g/dL), ferritin level was significantly low, and C-reactive protein andfibrinogen levels were significantly high in anemic obese patients.Increased cardiac pulse and echocardiographic findings, which may beindicative of early left ventricular diastolic dysfunction, were presentin these patients.Conclusion: Anemia may develop due to iron deficiency and chronicinflammation in obese adolescents. Even mild anemia may causeincreased heart rate and affect left ventricular diastolic functions.Diet programs for obese children should be carefully planned to avoidiron deficiency anemia, which may worsen the cardiac events in longterm follow-up.

Abstract

Amaç: Obez adölesanlarda aneminin kardiyovasküler bulgular üzerine etkisinin araştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya 29 anemik, 33 anemik olmayan obez adölesan ve 33 obez olmayan sağlıklı adölesan dahil edildi. Bu üç grup, anemi ve obesitenin klinik ve laboratuvar bulguları açısından değerlendirildi. Kardiyak fonksiyonları değerlendirmek için ekokardiyografi kullanıldı. Bulgular: Anemik obez hastalarda anemi hafifti (ortalama hemoglobin 11,67±0,79 g/dL), ferritin seviyesi anlamlı olarak düşük, C-reaktif protein ve fibrinojen düzeyleri anlamlı olarak yüksek bulundu. Bu grupta kardiyak nabız anemik olmayan obez adölesanlarınkine göre anlamlı yüksekti ve ekokardiyografik incelemede anemik obez grupta erken ventriküler diyastolik disfonksiyon göstergesi olabilecek bulgular saptandı. Sonuç: Obez adölesanlarda demir eksikliği ve kronik enflamasyona bağlı anemi gelişebilir. Hafif anemi varlığı bile kardiyak nabızda artışa ve sol ventrikül diyastolik fonksiyonlarında etkilenmeye neden olabilir. Bu nedenle obez çocuklarda uzun dönemde kalp fonksiyonlarının olumsuz yönde etkilenmemesi açısından diyet programları demir eksikliği anemisini önleyecek şekilde dikkatlice planlanmalıdır.

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Bu Makaleye Atıf Yap

YILDIRIM, Ö., DEMİRCAN, T., TÜFEKÇİ, Ö., KIZILCA, Ö., KUYUM, P., KIR, M., ABACI, A., ÜNAL, N., ARSLAN, N., BÖBER, E., YILMAZ, Ş., ÖREN, H. (2018). Anemia and Its Effect on Cardiovascular Findings in Obese Adolescents. Turkish Journal of Hematology, Cilt: 35 - Sayı: 3, 192–196. https://ajindex.com/articles/412431

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