Therefore,in the present study, the clinical manifestations, recent advancements in thegenetics of early onset IBD and the clinical approach to diagnoses of IBD inchildren are described.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Crohn’s disease and ulcerative colitis are immunologically mediated chronicinflammatory conditions, collectively referred to as inflammatory boweldiseases (IBD).
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Temel Bulgular & Veri:Since a significantproportion of patients diagnosed with IBD demonstrate their clinicalmanifestations during childhood, knowledge about the disease progression,severity and diagnosis in this particular patient population is crucial.
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Sonuç & Katkı:Therefore,in the present study, the clinical manifestations, recent advancements in thegenetics of early onset IBD and the clinical approach to diagnoses of IBD inchildren are described.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Özet
Crohn’s disease and ulcerative colitis are immunologically mediated chronicinflammatory conditions, collectively referred to as inflammatory boweldiseases (IBD). While most studies have described the condition in the adultpopulation, recent evidences suggest that IBD in children may represent anetiologically distinct disease from the adult onset IBD. Since a significantproportion of patients diagnosed with IBD demonstrate their clinicalmanifestations during childhood, knowledge about the disease progression,severity and diagnosis in this particular patient population is crucial. Therefore,in the present study, the clinical manifestations, recent advancements in thegenetics of early onset IBD and the clinical approach to diagnoses of IBD inchildren are described.
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Bu Makaleye Atıf Yap
MOAZZAMİ, B., MOAZZAMİ, K., REZAEI, N. (2019). Early onset inflammatory bowel disease: manifestations, genetics and diagnosis. Turkish Journal of Pediatrics, Cilt: 61 - Sayı: 5, 637–647. https://ajindex.com/articles/412072
Brant SR. Update on the heritability of inflammatory bowel disease: the importance of twin studies. Inflamm Bowel Dis 2011; 17: 1-5
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007; 448: 427-434
Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417-429
Sonnenberg A. Occupational distribution of inflammatory bowel disease among German employees. Gut 1990; 31: 1037-1040
Baldassano RN, Piccoli DA. Inflammatory bowel disease in pediatric and adolescent patients. Gastroenterol Clin North Am 1999; 28: 445-458
Feuerstein JD, Cheifetz AS. Ulcerative colitis: epidemiology, diagnosis, and management. Mayo Clin Proc 2014; 89: 1553-1563
Ye Y, Pang Z, Chen W, Ju S, Zhou C. The epidemiology and risk factors of inflammatory bowel disease. Int J Clin Exp Med 2015; 8: 22529-22542
Kugathasan S, Judd RH, Hoffmann RG, et al; Wisconsin Pediatric Inflammatory Bowel Disease Alliance. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J Pediatr 2003; 143: 525-531
Nieuwenhuis EE, Escher JC. Early onset IBD: what's the difference? Dig Liver Dis 2008; 40: 12-15
Olafsdottir EJ, Fluge G, Haug K. Chronic inflammatory bowel disease in children in western Norway. J Pediatr Gastroenterol Nutr 1989; 8: 454-458
Vind I, Riis L, Jess T, et a; DCCD Study Group. Increasing incidences of inflammatory bowel disease and decreasing surgery rates in Copenhagen City and County, 2003-2005: a population-based study from the Danish Crohn colitis database. Am J Gastroenterol 2006; 101: 1274-1282
Cosgrove M, Al-Atia RF, Jenkins HR. The epidemiology of paediatric inflammatory bowel disease. Arch Dis Child 1996; 74: 460-461
Benchimol EI, Fortinsky KJ, Gozdyra P, Van den Heuvel M, Van Limbergen J, Griffiths AM. Epidemiology of pediatric inflammatory bowel disease: a systematic review of international trends. Inflamm Bowel Dis 2011; 17: 423-439
Motil KJ, Grand RJ, Davis-Kraft L, Ferlic LL, Smith EO. Growth failure in children with inflammatory bowel disease: a prospective study. Gastroenterology 1993; 105: 681-691