Dergiler / Turkish Journal of Gastroenterology / 2020 / Cilt: 31 - Sayı: 11

Risk of colonoscopic post-polypectomy bleeding in patients after the discontinuation of antithrombotic therapy

Sayfa
752–759
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

No thromboembolic events were observed in either group.Conclusion: Our cessation periods were appropriate, and further shortening of these periods is possible.

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Amaç & Hipotez:Background/Aims: Few studies have examined the incidence of post-polypectomy bleeding (PPB) after discontinuation of antithrombotic therapies.
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Temel Bulgular & Veri:A total of 282 patients (540 polypectomies) discontinued antithrombotic agents (group 1), and 1,648 patients (2,827 polypectomies) did not take antithrombotic agents (group 2).
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Sonuç & Katkı:No thromboembolic events were observed in either group.Conclusion: Our cessation periods were appropriate, and further shortening of these periods is possible.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Background/Aims: Few studies have examined the incidence of post-polypectomy bleeding (PPB) after discontinuation of antithrombotic therapies. Therefore, this study aimed to evaluate the incidence of PPB and thromboembolic events in patients whose antithrombotic agents were discontinued before colonoscopy.Materials and Methods: We retrospectively selected all patients who underwent colon polypectomy at a community hospital. A total of 282 patients (540 polypectomies) discontinued antithrombotic agents (group 1), and 1,648 patients (2,827 polypectomies) did not take antithrombotic agents (group 2). The cessation periods before and after polypectomies were 4 and 3 days for warfarin, 5 and 3 days for anti-platelet agents, and 7 and 5 days of combination therapy, respectively. Main outcome measurements were the incidence of PPB and thromboembolic events.Results: Immediate PPB rates were 3.9% (11/282) in group 1 and 4.6% (76/1648) in group 2 (adjusted odds ratio [OR], 0.85; 95% confidence interval [CI], 0.42-1.72; p=0.65). Delayed PPB rates were 1.4% (4/282) in group 1 and 1.1% (18/1648) in group 2 (adjusted OR, 1.24; 95% CI, 0.36-4.24; p=0.732). No thromboembolic events were observed in either group.Conclusion: Our cessation periods were appropriate, and further shortening of these periods is possible.

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Bu Makaleye Atıf Yap

KISHINO, T., OYAMA, T., HOTTA, K., ISHII, E., MOMOI, T., SHIMIZU, T., KUNIEDA, K., TAKEDA, S., KOMATSU, H. (2020). Risk of colonoscopic post-polypectomy bleeding in patients after the discontinuation of antithrombotic therapy. Turkish Journal of Gastroenterology, Cilt: 31 - Sayı: 11, 752–759. https://ajindex.com/articles/410036

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Kaynakça (14)

  1. Fisher DA, Maple JT, Ben-Menachem T, et al. Complications of colonoscopy. Gastrointest Endosc 2011; 74: 745-52
  2. Levin TR, Zhao W, Conell C, et al. Complications of colonoscopy in an integrated health care delivery system. Ann Intern Med 2006; 145: 880-6
  3. Day LW, Kwon A, Inadomi JM, Walter LC, Somsouk M. Adverse events in older patients undergoing colonoscopy: a systematic re view and meta-analysis. Gastrointest Endosc 2011; 74: 885-96
  4. Rabeneck L, Saskin R, Paszat LF. Onset and clinical course of bleeding and perforation after outpatient colonoscopy: a popula tion-based study. Gastrointest Endosc 2011; 73: 520-3
  5. Crispin A, Birkner B, Munte A, Nusko G, Mansmann U. Process quality and incidence of acute complications in a series of more than 230,000 outpatient colonoscopies. Endoscopy 2009; 41:1018- 25
  6. Ko CW, Riffle S, Michaels L, et al. Serious complications within 30 days of screening and surveillance colonoscopy are uncommon. Clin Gastroenterol Hepatol 2010; 8: 166-73
  7. Rathgaber SW, Wick TM. Colonoscopy completion and complica tion rates in a community gastroenterology practice. Gastrointest Endosc 2006; 64: 556-62
  8. Veitch AM, Vanbiervliet G, Gershlick AH, et al. Endoscopy in pa tients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and Eu ropean Society of Gastrointestinal Endoscopy (ESGE) guidelines. Endoscopy 2016; 48: c1
  9. Pigo F, Bertani H, Grande G, Abate F, Vavassori S, Conigliaro RL. Post-polypectomy bleeding after colonoscopy on uninterrupted as pirin/non steroideal antiflammatory drugs: Systematic review and meta-analysis. Dig Liver Dis 2018; 50: 20-6
  10. Singh M, Mehta N, Murthy UK, Kaul V, Arif A, Newman N. Postpo lypectomy bleeding in patients undergoing colonoscopy on uninter rupted clopidogrel therapy. Gastrointest Endosc 2010; 71: 998-1005
  11. Palareti G, Legnani C, Guazzaloca G, Frascaro M, Grauso F, De Rosa F, Fortunato G, Coccheri S. Activation of blood coagulation after abrupt or stepwise withdrawal of oral anticoagulants--a pro spective study. Thromb Haemost 1994; 72: 222-6
  12. Maulaz AB, Bezerra DC, Michel P, Bogousslavsky J. Effect of dis continuing aspirin therapy on the risk of brain ischemic stroke. Arch Neurol 2005; 62: 1217-20
  13. Fujimoto K, Fujishiro M, Kato M, et al. Guidelines for gastroen terological endoscopy in patients undergoing antithrombotic treat ment. Dig Endosc 2014; 26: 1-14
  14. Acosta RD, Abraham NS, Chandr