KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Gastroenterology / 2014 / Cilt: 25 - Sayı: 5

Endoscopic papillectomy for carcinoma of the ampulla of Vater: Possible standardization based on endoscopy and immunohistochemistry

Hamada YOSHİHİRO
Maeshiro KENSEİ
Nakayama YOSHİFUKU
Sayfa
563–567
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Although endoscopic papillectomy might be indicated for the superficial-type lesions, caution is needed in the determination of the extent of luminal-type lesions.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Background/Aims: Clinicopathological investigation of the indications for the use of endoscopic papillectomy as a treatment for carcinoma in situ of the ampulla of Vater (CAV).Materials and Methods: Of 97 patients diagnosed with CAV in our department over the last 15 years, the 5 patients who received a carcinoma in situ diagnosis and were included in this retrospective study.
📊
Temel Bulgular & Veri:Immunohistochemical staining showed that the superficial-type lesions were positive for cytokeratin 20, suggesting development of the cancer from the Ad.
💡
Sonuç & Katkı:Although endoscopic papillectomy might be indicated for the superficial-type lesions, caution is needed in the determination of the extent of luminal-type lesions.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Background/Aims: Clinicopathological investigation of the indications for the use of endoscopic papillectomy as a treatment for carcinoma in situ of the ampulla of Vater (CAV).Materials and Methods: Of 97 patients diagnosed with CAV in our department over the last 15 years, the 5 patients who received a carcinoma in situ diagnosis and were included in this retrospective study. Results: The lesions in the patients were classified as either the superficial or luminal type, based on endoscopic findings. Histological findings showed that the major duodenal papilla (Ad) was the main site of CAV in the superficial type and that the common duct into the duodenal lumen (Ac) was the primary site in the luminal type. Immunohistochemical staining showed that the superficial-type lesions were positive for cytokeratin 20, suggesting development of the cancer from the Ad. The luminal-type lesion was positive for cytokeratin 7 and negative for cytokeratin 20, suggesting an origin in the pancreatobiliary duct. Mucin-2 was expressed in the superficial type, and mucin-1 in the luminal type. Conclusion: Superficial-type lesions, which are principally located in the Ad, exhibit little tendency to invade surrounding tissues, whereas the luminal-type lesions, which are predominantly located in the Ac, may tend to be more invasive. Although endoscopic papillectomy might be indicated for the superficial-type lesions, caution is needed in the determination of the extent of luminal-type lesions.

🔖

Bu Makaleye Atıf Yap

YOSHİHİRO, H., KENSEİ, M., YOSHİFUKU, N. (2014). Endoscopic papillectomy for carcinoma of the ampulla of Vater: Possible standardization based on endoscopy and immunohistochemistry. Turkish Journal of Gastroenterology, Cilt: 25 - Sayı: 5, 563–567. https://ajindex.com/articles/409538

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Ponchon T, Berger F, Chavaillon A, Bory R, Lambert R. Contribu- tion of endoscopy to diagnosis and treatment of tumors of the ampulla of vater. Cancer 1989; 64: 161-7.
  2. Catalano MF, Linder JD, Chak A, et al. Endoscopic management of adenoma of the major duodenal papilla. Gastrointesti Endosc 2004; 59: 225-32.
  3. Moriya T, Kimura W, Hirai I, et al. Total papillectomy for border- line malignant tumor of papilla of vater. Hepatogastroenterology 2004; 51: 859-61.
  4. Ito K, Fujita N, Noda Y, et al. Case of early ampullary cancer treated by endoscopic papillectomy. Dig Endosc 2004; 16: 157-61.
  5. Binmoeller KF, Boaventura S, Ramsperger K, Soehendra N. Endo- scopic snare excision of benign adenomas of the papilla of Vater. Gastrointest Endosc 1993; 39: 127-31.
  6. Zhou H, Schaefer N, Wolff M, Fischer HP. Carcinoma of the am- pulla of Vater: comparative histologic/immunohistochemical classification and follow-up. Am J Surg Pathol 2004; 28: 875-82.
  7. Matsubayashi H, Watanabe H, Yamaguchi T, et al. Differences in mucus and K-ras mutation in relation to phenotypes of tumors of the papilla of Vater. Cancer 1994; 86: 596-607.
  8. Kitamura H, Yonezawa S, Tanaka S, Kim YS, Sato E. Expression of mucin carbohydrates and core proteins in carcinomas of the am- pulla of Vater: their relationship to prognosis. Jpn J Cancer Res 1996; 87: 631-40. Japanese Society of Biliary Surgery. Classification of Biliary Tract Carcinoma. 2nd English Edition. Tokyo: Kanehara & Co, 2004;
  9. Yamaguchi K, Enjoji M. Carcinoma of the ampulla of Vater. A clini- copathologic study and pathologic staging of 109 cases of carci- noma and 5 cases of adenoma. Cancer 1987; 59: 506-15.
  10. Cubilla AL, Fitzgerald PJ. Surgical pathology aspects of cancer of the ampulla-head of pancreas region. Monogr Pathol 1980; 21: 67-81.
  11. Wise L, Pizzimbono C, Dehner LP. Periampullary cancer. A clini- copathologic study of sixty-two patients. Am J Surg 1976; 131: 141-8. Rosai J. Gross techniques in surgical pathology. In: Rosai J, editor. Rosai and Ackerman's Surgical Pathology. 9th ed. St. Louis: Mosby; 2004. Rosai J. Gallbladder and extrahepatic bile duct. In: Rosai J, editor. Rosai and Ackerman's Surgical Pathology, 9th ed. St. Louis: Mosby; 2004. Tot T. Adenocarcinomas metastatic to the liver: the value of cy- tokeratins 20 and 7 in the search for unknown primary tumors. Cancer 1999; 85: 171-7.
  12. Alexander J, Krishnamurthy S, Kovacs D, et al. Cytokeratin profile of extrahepatic pancreaticobiliary epithelia and their carcinomas. Appl Immunohistoche