Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightThe development of H. pylori infection was independently related to children with one parent only [odd ratio (OR),9.04; 95% confidence interval (CI), 1.29-62.89; p<0.001], living in houses without sanitary facilities (OR, 3.88; 95% CI, 1.27-14.22;p=0.016), belonging to low-income families (OR, 8.52; 95% CI, 2.52-71.39; p=0.002), and of parents with a prior history of gastritis(OR, 2.68; 95% CI, 1.49-14.50; p=0.004).Conclusion: Children with CD and H. pylori infection had milder forms of enteropathy compared to children who are negative for H.pylori, suggesting that H. pylori infection may confer some protection against the development of severe degrees of villous atrophy
📌 3 Maddede Bu Makale
Özet
Background/Aims: The relationship between Helicobacter pylori and celiac disease (CD) remains controversial. The aim of thisstudy was to assess the prevalence and risk factors for H. pylori infection among children diagnosed with CD.Materials and Methods: This study included 70 patients diagnosed with CD at a tertiary referral center in Romania. Age, gender,and indicators of environmental conditions were evaluated via interviews with the children’s caretakers. A multivariable logisticregression analysis was performed to identify the independent predictors for H. pylori infection.Results: Of the 70 patients, 37 (52.9%) were females, and the mean age was 4.04±3.26 years. H. pylori infection was diagnosedin 23 (32.8%) patients, of whom 12 (52.1%) were females, and the mean age was 6.2±4.5 years. Of the total number of childrenwith CD and H. pylori infection, 18 (78.2%) had milder forms of enteropathy (Marsh I-II), whereas the remaining 5 (21.7%) hadvillous atrophy compared to the other 47 (67.2%) patients who were negative for H. pylori-infection and showed more severe intestinal damage. The development of H. pylori infection was independently related to children with one parent only [odd ratio (OR),9.04; 95% confidence interval (CI), 1.29-62.89; p<0.001], living in houses without sanitary facilities (OR, 3.88; 95% CI, 1.27-14.22;p=0.016), belonging to low-income families (OR, 8.52; 95% CI, 2.52-71.39; p=0.002), and of parents with a prior history of gastritis(OR, 2.68; 95% CI, 1.49-14.50; p=0.004).Conclusion: Children with CD and H. pylori infection had milder forms of enteropathy compared to children who are negative for H.pylori, suggesting that H. pylori infection may confer some protection against the development of severe degrees of villous atrophy