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Dergiler / Ulusal Travma ve Acil Cerrahi Dergisi / 2021 / Cilt: 27 - Sayı: 6

Treatment of open wounds secondary to trauma using polyurethane foams with boric acid particles

Hasan Ulaş OĞUR
Rana KAPUKAYA
Osman ÇİLOĞLU
Özgür KÜLAHÇI
Volkan Tolga TEKBAŞ
Abdülkerim YÖRÜKOĞLU
Sayfa
624–630
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The use of new foams with boric acid particles combined with the NPWT system may be a good alternative method in the treatment of open wounds due to trauma.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:BACKGROUND: To investigate the efficacy of new foams with boric acid particles combined with a negative pressure wound treatment (NPWT) system in open fractures with tissue defects secondary to trauma.
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Temel Bulgular & Veri:METHODS: Forty-nine patients with open fractures secondary to trauma with soft tissue defects who were admitted between 2016 and 2018 were included in the study.
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Sonuç & Katkı:The use of new foams with boric acid particles combined with the NPWT system may be a good alternative method in the treatment of open wounds due to trauma.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

BACKGROUND: To investigate the efficacy of new foams with boric acid particles combined with a negative pressure wound treatment (NPWT) system in open fractures with tissue defects secondary to trauma. METHODS: Forty-nine patients with open fractures secondary to trauma with soft tissue defects who were admitted between 2016 and 2018 were included in the study. Patients were examined in two groups. In Group 1, boric acid-impregnated foams combined with the NPWT system were used in 27 patients, and in Group 2, silver nitrate-impregnated foams combined with NPWT systems were used in 22 patients. In addition to evaluating the broad-spectrum antibacterial feature of silver nitrate, the antimicrobial, angiogenetic, and epithelializing effects of boric acid were investigated macroscopically and histopathologically. RESULTS: A reduction in wound size and granulation was observed in each group. Macroscopically, the reduction in wound size, epithelialization and granulation were pronounced in Group 1 and in Group 2. Microscopically, the number of fibroblasts, collagen synthesis, and angiogenesis were significantly increased in Group 1 compared with Group 2. CONCLUSION: In this clinical trial, both the broad spectrum antimicrobial feature of boric acid and its positive effect on the cells responsible for wound healing were found to be an alternative compared with silver nitrate. The use of new foams with boric acid particles combined with the NPWT system may be a good alternative method in the treatment of open wounds due to trauma.

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Bu Makaleye Atıf Yap

OĞUR, H. U., KAPUKAYA, R., ÇİLOĞLU, O., KÜLAHÇI, Ö., TEKBAŞ, V. T., YÖRÜKOĞLU, A. (2021). Treatment of open wounds secondary to trauma using polyurethane foams with boric acid particles. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 27 - Sayı: 6, 624–630. https://ajindex.com/articles/401950

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Kaynakça (15)

  1. Huang C, Leavitt T, Bayer LR, Orgil DP. Effect of negative pressure wound therapy on wound healing. Currn Probl Surg 2014;51:301–31
  2. Putnis S, Khan WS, Wong JML. Negative pressure wound therapy-a review of its uses in orthopaedic trauma. Open Orthop J 2014;8:142–7
  3. Orgill DP, Manders EK, Sumpio BE, Lee RC, Attinger CE, Gurtner GC, et al. The mechanisms of action of vacuum assisted closure: More to learn. Surgery 2009;146:40–51
  4. Gaisford S, Beezer AE, Bishop AH, Walker M, Parsons D. An in vitro method for the quantitative determination of the antimicrobial efficacy of silver-containing wound dressings. Int J Pharm 2009;336:111–6
  5. Sigel HJ, Herrera DF, Gay J. Silver negative pressure dressing with vacuum-assisted closure of massive pelvic and extremity wounds. Clin Orthop Relat Res 2014;472:830–5
  6. McDonnell G, Russell AD. Antiseptics and disinfectants: Activity, action, and resistance. Clin Microbiol Rev 1999;12:147–79
  7. Borrelly J, Blech M, Grosdidier G, Martin-Thomas C, Hartemann P. Contribution of a 3% solution of boric acid in the treatment of deep wounds with loss of substance. Ann Chir Plast Esthet 1991;36:65–9
  8. Tepedelen BE, Soya E, Korkmaz M. Boric acid reduces the formation of DNA double-strand breaks and accelerates wound healing process. Biol Trace Elem Res 2016;174:309–18
  9. Nzietchueng RM, Dousset B, Franck P, Benderdour M, Nabet P, Hess K. Mechanisms implicated in the effects of boron on wound healing. J Trace Elem Med Biol 2002;16:239–44
  10. Gupta A, Kumar P. Assessment of the histological state of the healing wound. Plast Aesthet Res 2015;2:239–42
  11. Scherer S, Pietramaggiori G, Mathews J, Prsa MJ, Huang S, Orgill DP. The mechanism of action of the vacuum assisted closure device. Plast Reconstr Surg 2008;122:786–97
  12. Ingber DE. The mechanochemical basis of cell and tissue regulation. Mech Chem Biosyst 2004;1:53–68
  13. Osterhoff G, Zwolak P, Kruger C, Wilzeck V, Simmen HP, Jukema GN. Risk factors for prolonged treatment and hospital readmission in 280 cases of negative-pressure wound therapy. J Plastic Reconstr Aesth Surg 2014;67:629–33
  14. Liu X, Zhang H, Cen S, Huang F. Negative pressure wound therapy versus conventional wound dressings in treatment of open fractures: A systematic review and meta-analysis. Int J Surg 2018;53:72–9
  15. Sudmann E, Vik H, Rait M, Todnem K, Andersen KJ, Julsham K, et al. Systemic and local silver accumulation after total hip replacement using silver-impregnated bone cement. Med Pr