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Dergiler / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 5

Association between maternal ghrelin levels and hyperemesis gravidarum

İkbal KAYGUSUZ
İlknur İNEGÖL GÜMÜŞ
Melahat YILDIRIM
Hüsamettin ERDAMAR
Sayfa
790–794
Yayın Tarihi
2013-05-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG).
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Temel Bulgular & Veri:Included in the study were 35 women with HG and 31 pregnant women without HG as a control group.
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Sonuç & Katkı:Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Hyperemesis gravidarum · pregnancy · ghrelin

Özet

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

Abstract

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

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Bu Makaleye Atıf Yap

KAYGUSUZ, İ., GÜMÜŞ, İ. İ., YILDIRIM, M., ERDAMAR, H. (2013). Association between maternal ghrelin levels and hyperemesis gravidarum. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 5, 790–794. https://ajindex.com/articles/400878

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Kaynakça (11)

  1. Wegrzyniak LJ, Repke JT, Ural SH. Treatment of hyperemesis gravidarum. Rev Obstet Gynecol 2012; 5: 78–84. Bailit JL. Hyperemesis gravidarum: epidemiologic findings from a large cohort. Am J Obstet Gynecol 2005; 193: 811–4.
  2. Verberg MF, Gillott DJ, Al-Fardan N, Grudzinskas JG. Hyperemesis gravidarum, a literature review. Hum Reprod Update 2005; 11: 527–39.
  3. Cummings DE, Shannon MH. Roles for ghrelin in the regulation of appetite and body weight. Arch Surg 2003; 138: 389–96.
  4. Aydın S, Geçgil H, Kılıç N, Erman F, Kılıç SS, Yeşilada Ö. Is ghrelin a natural anti-microbial agent? Turk J Med Sci 2008; 38: 1 Shintani M, Ogawa Y, Ebihara K, Aizawa-Abe M, Miyanaga F, Takaya K, Hayashi T, Inoue G, Hosoda K, Kojima M et al. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes 2001; 50: 227–32.
  5. Tschöp M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R, Folwaczny C. Post-prandial decrease of circulating human ghrelin levels. J Endocrinol Invest 2001; 24: 19–21.
  6. De Vriese C, Delporte C. Ghrelin: a new peptide regulating growth hormone release and food intake. Int J Biochem Cell Biol 2008; 40: 1420–4.
  7. Temel İ, Çelik Ö, Hasçalık S, Çelik N, Şahin İ, Aydın S. Serum nonesterified fatty acids, ghrelin, and homocysteine levels in women with polycystic ovary syndrome. Turk J Med Sci 2010; 40: 221–8.
  8. Barreiro ML, Tena-Sempere M. Ghrelin and reproduction: a novel signal linking energy status and fertility? Mol Cell Endocrinol 2004; 226: 1–9. Tena-Sempere M. Exploring the role of ghrelin as novel regulator of gonadal function. Growth Horm IGF Res 2005; 15: 83– Gualillo O, Caminos J, Blanco M, Garcia-Caballero T, Kojima M, Kangawa K, Dieguez C, Casanueva F. Ghrelin, a novel placental-derived hormone. Endocrinology 2001; 142: 788–94.
  9. Steier JA, Bergsjo PB, Thorsen T, Myking OL. Human chorionic gonadotropin in maternal serum in relation to fetal gender and utero-placental blood flow. Acta Obstet Gynecol Scand 2004; 83: 170–4.
  10. Wibowo N, Purwosunu Y, Sekizawa A, Farina A, Tambunan V, Bardosono S. Vitamin B 6 supplementation in pregnant women with nausea and vomiting. Int J Gynaecol Obstet 2012; 116: 206–10.
  11. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized doubleblind controlled trial. J Med Assoc Thai 2007; 90: