KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Medical Sciences / 2014 / Cilt: 44 - Sayı: 1

The diagnostic value of ischemia-modified albumin in the diagnosis of aortic pathology

Oğuz EROĞLU
Süha TÜRKMEN
Ahmet MENTEŞE
Gökalp ALTUN
Süleyman TÜREDİ
Umut ERYİĞİT
Süleyman Caner KARAHAN
Abdülkadir GÜNDÜZ
Sayfa
62–67
Yayın Tarihi
2014-05-18
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm.
📊
Temel Bulgular & Veri:Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography.
💡
Sonuç & Katkı:This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Ischemia-modified albumin · aortic aneurysm · aortic dissection

Özet

To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.

Abstract

To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.

🔖

Bu Makaleye Atıf Yap

EROĞLU, O., TÜRKMEN, S., MENTEŞE, A., ALTUN, G., TÜREDİ, S., ERYİĞİT, U., KARAHAN, S. C., GÜNDÜZ, A. (2014). The diagnostic value of ischemia-modified albumin in the diagnosis of aortic pathology. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 1, 62–67. https://ajindex.com/articles/394089

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Kayan M, Yavuz T, Etli M, Benzin Ş, İbişoğlu S, Üstün ED, Köroğlu M, Ceylan E, Sağlam U. Endovascular treatment of abdominal aortic aneurysms with Endologix® stent graft: single-site experiences. Turk J Med Sci 2012; 42: 823–9.
  2. Yuan SM, Shi YH, Wang JJ, Lü FQ, Gao S. Elevated plasma D-dimer and hypersensitive C-reactive protein levels may indicate aortic disorders. Rev Bras Cir Cardiovasc 2011; 26: 573–81.
  3. Moriyama Y, Toyohira H, Koga M, Watanabe S, Saigenji H, Shimokawa S, Taira A. Influence of aortic dissection on the clotting-fibrinolysis system and platelet function. Int J Angiol 1998; 7: 65–7.
  4. Keating L, Benger JR, Beetham R, Bateman S, Veysey S, Kendall J, Pullinger R. The PRIMA study: presentation ischemiamodified albumin in the emergency department. Emerg Med J 2006; 23: 764–8.
  5. Weber T, Högler S, Auer J, Berent R, Lassnig E, Kvas E, Eber B. D-dimer in acute aortic dissection. Chest 2003; 123: 1375–8.
  6. Suzuki T, Distante A, Zizza A, Trimarchi S, Villani M, Salerno Uriarte JA, De Luca Tupputi Schinosa L, Renzulli A, Sabino F, Nowak R et al. Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience. Circulation 2009; 119: 2702–7.
  7. Sbarouni E, Georgiadou P, Marathias A, Geroulanos S, Kremastinos DT. D-dimer and BNP levels in acute aortic dissection. Int J Cardiol 2007; 122: 170–2.
  8. Turedi S, Gunduz A, Mentese A, Topbas M, Karahan SC, Yeniocak S, Turan I, Eroglu O, Ucar U, Karaca Y et al. The value of ischemia-modified albumin compared with d-dimer in the diagnosis of pulmonary embolism. Respir Res 2008; 30: 9–49.
  9. Abboud H, Labreuche J, Meseguer E, Lavallee PC, Simon O, Olivot JM, Mazighi M, Dehoux M, Benessiano J, Steg PG et al. Ischemia-modified albumin in acute stroke. Cerebrovasc Dis 2007; 23: 216–20. Zuwała-Jagiełło J, Warwas M, Pazgan-Simon M. Ischemiamodified albumin (IMA) is increased in patients with chronic hepatitis C infection and related to markers of oxidative stress and inflammation. Acta Biochim Pol 2012; 59: 661–7.
  10. Prydz H, Camerer E, Rottingen JA, Wiiger MT, Gjernes E. Cellular consequences of the initiation of blood coagulation. Thromb Haemost 1999; 82: 183–92.
  11. Peacock F, Morris DL, Anwaruddin S, Christenson RH, Collinson PO, Goodacre SW, Januzzi JL, Jesse RL, Kaski JC, Kontos MC et al. Meta-analysis of ischemia-modified albumin to rule out acute coronary syndromes in the emergency department. Am Heart J 2006; 152: 253–62.
  12. Bar-Or D, Winkler JV, Vanb