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Dergiler / Turkish Journal of Medical Sciences / 2014 / Cilt: 44 - Sayı: 2

Evaluation of hepatocellular carcinoma with computed tomography perfusion imaging

Ümmügülsüm BAYRAKTUTAN
Abdulmecit KANTARCI
Hayri OĞUL
Yeşim KIZRAK
Ömer ÖZYİĞİT
Zeyneb YÜCELER
Berhan GENÇ
Bünyami ÖZOĞUL
Sayfa
193–196
Yayın Tarihi
2014-05-18
DOI
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Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC).
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Temel Bulgular & Veri:Materials and methods: Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT.
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Sonuç & Katkı:Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Computed tomography · perfusion imaging · hepatocellular carcinoma

Özet

To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC). Materials and methods: Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT. Perfusion parameters of blood flow (BF), blood volume (BV), arterial perfusion (AP), portal perfusion (PP), and hepatic perfusion index (HPI) were calculated in the normal liver parenchyma and HCC samples. Results: A total of 21 histologically proven HCC lesions were evaluated from CT perfusion images. BF, BV, AP, and HPI values were shown to be significantly higher (P < 0.05) in the HCC lesions than in the normal liver parenchyma. Conversely, PP values were found to be significantly lower (P < 0.05) in HCC relative to liver parenchyma. Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.

Abstract

To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC). Materials and methods: Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT. Perfusion parameters of blood flow (BF), blood volume (BV), arterial perfusion (AP), portal perfusion (PP), and hepatic perfusion index (HPI) were calculated in the normal liver parenchyma and HCC samples. Results: A total of 21 histologically proven HCC lesions were evaluated from CT perfusion images. BF, BV, AP, and HPI values were shown to be significantly higher (P < 0.05) in the HCC lesions than in the normal liver parenchyma. Conversely, PP values were found to be significantly lower (P < 0.05) in HCC relative to liver parenchyma. Conclusion: CT perfusion imaging has the ability to evaluate tumor assessment, characterization, and neoangiogenesis in HCC.

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Bu Makaleye Atıf Yap

BAYRAKTUTAN, Ü., KANTARCI, A., OĞUL, H., KIZRAK, Y., ÖZYİĞİT, Ö., YÜCELER, Z., GENÇ, B., ÖZOĞUL, B. (2014). Evaluation of hepatocellular carcinoma with computed tomography perfusion imaging. Turkish Journal of Medical Sciences, Cilt: 44 - Sayı: 2, 193–196. https://ajindex.com/articles/383227

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