Dergiler / Turkish Journal of Urology / 2017 / Cilt: 43 - Sayı: 3

Effective predictors for surgical decision in antenatal hydronephrosis: a prospective multiparameter analysis

Antenatal hidronefrozlarda ameliyat kararında etkili belirleyiciler: ileriye dönük çok değişkenli analiz

Sayfa
361–365
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

These parameters can be used for appropriate management of antenatalhydronephrosis.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: The majority of antenatal hydronephrosis disappears spontaneously.
📊
Temel Bulgular & Veri:In our study, we haveinvestigated the effective predictors for surgical decision in antenatal hydronephrosis.Material and methods: Forty-four patients found to have renal pelvic anteroposterior (AP) diametermore than 10-mm on antenatal ultrasonograpy were followed after birth.
💡
Sonuç & Katkı:These parameters can be used for appropriate management of antenatalhydronephrosis.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: The majority of antenatal hydronephrosis disappears spontaneously. In our study, we haveinvestigated the effective predictors for surgical decision in antenatal hydronephrosis.Material and methods: Forty-four patients found to have renal pelvic anteroposterior (AP) diametermore than 10-mm on antenatal ultrasonograpy were followed after birth. The study groups were dividedinto two groups: follow-up and surgery group. On follow-up, longitudinal diameter of the kidney,parenchymal thickness of the kidney, AP diameter of renal pelvis, AP diameter of middle calyces onultrasonograpy, and differential renal function, 20th minute clearance, half-life of radionuclide tracer(T1/2), Tmax, Tmax-T1/2, normalised residual activity (NORA) on diuretic renography were evaluated.Ultrasonograpy and diuretic renography measurements were compared in patients whose hydronephrosisresolve or proceeded to surgery.Results: Forty-four patients were diagnosed as antenatal hydronephrosis, spontaneous resolution occurredin 23 (52%), and surgery was performed in 21 patients (48%). Mean age at operation was 8.5±6.5months (3-24 months). Mean AP diameter of renal pelvis was 29.5±14.2 mm for surgery group, 13.6±4.2mm for follow-up group (p<0.001). Univariate analyses showed significance for all ultrasonographicmeasurements and only the differential renal function by diuretic renography. Multivariate logisticregression analysis showed significance for AP diameter of renal pelvis (odds ratio 1.37; 95% Cl 1.13-1.66), and differential renal function (odds ratio 1.14; 95% Cl 1.01-1.29).Conclusion: AP diameter of renal pelvis and differential renal function were the most effective parametersfor surgical decision. These parameters can be used for appropriate management of antenatalhydronephrosis.

Abstract

Amaç: Antenatal hidronefroz (AHN)’ların birçoğu doğumdan sonra kendiliğinden gerilemektedir. Çalışmamızda AHN’ların takibinde alınan ameliyat kararında etkili belirteçler araştırıldı. Gereç ve yöntemler: Antenatal ultrasonografi (USG)’de renal pelvis anterior posterior (AP) çapı 10-mm’den fazla olan hastalar doğumdan sonra takip edildiler. USG’de, böbreğin uzun ekseni, böbrek parankim kalınlığı, renal pelvis AP çapı, orta kaliks AP çapı; diüretik renografi (DRG)’de, diferansiyel renal fonksiyon, 20. dakika klirens, T1/2, Tmax, Tmax-T1/2, normalleştirilmiş artık etkinlik (NORA: normalised residual activity) değerlendirildi. Takip sırasında hidronefrozu gerileyen veya ameliyat edilen hastalarda USG ve DRG ölçümleri karşılaştırıldı. Bulgular: AHN tanısı alan 44 hastanın 23’ünde (%52) hidronefroz kendiliğinden geriledi, 21’inde (%48) ameliyat yapıldı. Ortalama ameliyat yaşı 8,5 ay (3-24 ay) idi. Renal pelvis AP çapı takip grubunda 13,6±4,2 mm, ameliyat grubunda 29,5±14,2 mm hesaplandı (p<0,001). Tek değişkenli analizde, ameliyat kararının alınmasında USG ölçümlerinin tümü, DRG ölçümlerinden sadece diferansiyel renal fonksiyon anlamlı bulundu. Çok değişkenli lojistik regresyon analizinde, renal pelvis AP çapı (odds ratio 1,37; %95 Cl 1,13-1,66) ve diferansiyel renal fonksiyon (odds ratio 1,14; %95 Cl 1,01-1,29) anlamlı bulundu. Sonuç: AHN’larda ameliyat kararının alınmasında en etkili belirteçlerin renal pelvis AP çapı ve diferansiyel renal fonksiyon olduğu bulundu. Bu ölçümler uygun tedavi stratejilerin oluşturulmasında yardımcı olabilir.

🔖

Bu Makaleye Atıf Yap

KILLI, İ., AVLAN, D., KARA, P. P., APAYDIN, F. D., DELİBAŞ, A., NAYCI, A. (2017). Effective predictors for surgical decision in antenatal hydronephrosis: a prospective multiparameter analysis. Turkish Journal of Urology, Cilt: 43 - Sayı: 3, 361–365. https://ajindex.com/articles/379623

Kaynakça (1)

  1. Nguyen HT, Herndon CD, Cooper C, Gatti J, Kirsch A, Kokorowski P, et al. The society for fetal urology consensus statement on the evaluation and management of antenatal hydro-nephrosis. J Pediatr Urol 2010;6:212-31. [CrossRef] 2. Onen A. Treatment and outcome of prenatally detected newborn hydronephrosis. J Pediatr Urol 2007;3:469-76. [CrossRef] 3. Lee RS, Cendron M, Kinnamon DD, Nguyen HT. Antenatal hydronephrosis as a predictor of postnatal outcome: a meta analysis. Pediatrics 2006;118:586-93. [CrossRef] 4. Dudley JA, Haworth JM, McGraw ME, Frank JD, Tizard EJ. Clinical relevance and implications of antenatal hydronephrosis. Arch Dis Child Fetal Neonatal Ed 1997;76:F31-4. 5. Rickwood AM, Reiner I. Urinary stone formation in children with prenatally diagnosed uropathies. Br J Urol 1991;68:541-2. [CrossRef] 6. Longpre M, Nguan A, Macneily AE, Afshar K. Prediction of the outcome of antenatally diagnosed hydronephrosis: a multivariab-le analysis. J Pediatr Urol. 2012;8:135-9. [CrossRef] 7. Ransley PG, Manzonia GA. Postnatal management of UPJ obs-truction detected antenatally. Dialogues Pediatr Urol 1985;8:6. 8. Passerotti CC, Kalish LA, Chow J, Passerotti AM, Recabal P, Cendron M, et al. The predictive value of the first postnatal ult-rasound in children with antenatal hydronephrosis, J Pediatr Urol 2011;7:128-36. 9. Koff SA, Peller PA, Young DC, Pollifrone DL. The assess-ment of obstruction in the newborn with unilateral hydro-nephrosis by measuring the size of the opposite kidney. J Urol 1994;152:596-9. [CrossRef]