Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightThe decrease in AFC levels was also significantly higher in group A than in group B (p=0.044).Conclusion: Laparoscopic stripping has destructive effects on serum AMH levels and the operated side AFC levels after surgery for patients with endometrioma and dermoid cysts, and laparoscopic excision of endometrioma has more destructive effects on ovarian reserve than dermoid cysts.
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Özet
Objective: To compare the effects of laparoscopic cystectomy on ovarian reserve between women with endometrioma and dermoid cyst. Materials and Methods: Thirty-six patients were diagnosed as having endometrioma (group A) and 32 patients with dermoid cyst (group B) using ultrasonography. Preoperative anti-mullerian hormone (AMH) levels were measured and unilateral antral follicle counts (AFC) were calculated for the ovary side containing the cyst. Laparoscopic cystectomy was performed using the stripping technique for all participants. After 3 months, all participants were side containing the cyst. Laparoscopic cystectomy was performed using the stripping technique for all participants. After 3 months, all participants were Results: The mean serum preoperative AMH level and AFC level were significantly lower in group A than in group B (p=0.001, p=0.002), respectively. At 3 months after the surgery, serum AMH levels decreased significantly in group A from 2.04±0.68 to 1.47±0.55 (p=0.001), and from 2.60±0.57 to 2.17±0.56 in group B (p=0.001). In group A, unilateral (operated side) AFC levels decreased significantly from 4.05±1.24 to 2.16±0.94 (p=0.001), and in group B, it decreased significantly from 4.93±0.94 to 3.40±0.87 (p=0.001). The decrease in AMH levels was significantly higher in group A than in group B (p=0.033). The decrease in AFC levels was also significantly higher in group A than in group B (p=0.044).Conclusion: Laparoscopic stripping has destructive effects on serum AMH levels and the operated side AFC levels after surgery for patients with endometrioma and dermoid cysts, and laparoscopic excision of endometrioma has more destructive effects on ovarian reserve than dermoid cysts.
Abstract
Amaç: Laparoskopik kistektominin ovaryan rezerv üzerine etkisini endometriomalı ve dermoid kistli hastalarda karıştırmaktır. Gereç ve Yöntemler: Ultrasonografik olarak preoperatif tanı konulmuş 36 endometriomalı (grup A) ve 32 dermoid kistli (grup B) hasta çalışmaya alındı. Preoperatif anti-mullerian hormon (AMH) ve kistin olduğu overdeki antral folikül sayıları (AFC) ölçüldü. Tüm hastalara laparoskopik kistektomi stripping tekniği uygulanarak yapıldı. Ameliyattan 3 ay sonra tüm hastaların AMH ve AFC ölçümleri siklusun 3. ve 6. günleri arası tekrar yapıldı. Bulgular: Preoperatif serum AMH seviyeleri ve opere olan taraftaki AFC değerleri grup A’da grup B’de göre anlamlı derecede düşük saptandı [(p=0,001),(p=0,002)], sırasıyla. Ameliyattan 3 ay sonra serum AMH seviyesi grup A’da 2,04±0,68’den 1,47±0,55’e (p=0,001), grup B’de 2,60±0,57’den 2,17±0,56’ya (p=0,001) düştü. AFC seviyesi grup A’da ameliyattan 3 ay sonra 4,05±1,24’ten 2,16±0,94’e, grup B’de 4,93±0,94’den 3,40±0,87’ye (p=0,001) düşmüştür. AMH seviyesindeki düşüş grup A’da grup B’ye göre anlamlı derecede daha fazla olarak görüldü (p=0,033). AFC değerindeki düşüş grup A’da grup B’ye göre anlamlı oranda daha fazla idi (p=0,044). Sonuç: Laparoskopik stripping tekniği hem endometriomalı hem de dermoid kistli hastalarda serum AMH ve opere olan taraftaki AFC seviyeleri üstünde yıkıcı etkilere sahiptir. Endometriomaların laparoskopik olarak çıkartılması ovaryan rezerv üzerine dermoid kistlere göre daha yıkıcı etkilere sahiptir.