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Dergiler / Turkish Journal of Endocrinology and Metabolism / 2020 / Cilt: 24 - Sayı: 1

Development of Hypocalcemia Due to Targeted Therapies

Hedefe Yönelik Tedavilere Bağlı Gelişen Hipokalsemi

Asena GÖKÇAY CANPOLAT
Sule CANLAR
Berna İmge AYDOĞAN
Sevim GÜLLÜ
Murat Faik ERDOĞAN
Sayfa
105–108
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Herein, we describe two of our patients that displayed hypoparathyroidism and were treated with epidermal growth factor receptor (EGFR) inhibitor erlotinib, vascular endothelial growth factor receptor, and EGFR inhibitor vandetanib.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Novel biological agents are available for the treatment of malignancies, and apart from their utility, they may also have several side effects.
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Temel Bulgular & Veri:The effects on the endocrine system are frequently observed, among which thyroid dysfunctions are common and well-characterized, whereas parathyroid dysfunctions are rare and not well characterized.
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Sonuç & Katkı:Herein, we describe two of our patients that displayed hypoparathyroidism and were treated with epidermal growth factor receptor (EGFR) inhibitor erlotinib, vascular endothelial growth factor receptor, and EGFR inhibitor vandetanib.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Novel biological agents are available for the treatment of malignancies, and apart from their utility, they may also have several side effects. The effects on the endocrine system are frequently observed, among which thyroid dysfunctions are common and well-characterized, whereas parathyroid dysfunctions are rare and not well characterized. Herein, we describe two of our patients that displayed hypoparathyroidism and were treated with epidermal growth factor receptor (EGFR) inhibitor erlotinib, vascular endothelial growth factor receptor, and EGFR inhibitor vandetanib.

Abstract

Malignitelerin tedavisinde kullanılmakta olan yeni biyolojik ajanların yararlarının yanı sıra, birtakım yan etkileri de mevcuttur. Endokrin sistem üzerine sıklıkla etkiler görülmektedir ve bu etkiler arasında tiroid disfonksiyonu en sık olan ve en iyi tanımlanmış etki iken; paratiroid disfonksiyonu nadirdir ve iyi tanımlanamamıştır. Burada, epidermal büyüme faktörü reseptörü (EBFR) inhibitörü erlotinib ve hem vasküler endotelyal büyüme faktör reseptörü hem EBFR inhibitörü olan vandetanib ile tedavi edilen 2 olgumuzda gelişen hipoparatiroidizm tablosunu tanımladık.

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Bu Makaleye Atıf Yap

CANPOLAT, A. G., CANLAR, S., AYDOĞAN, B. İ., GÜLLÜ, S., ERDOĞAN, M. F. (2020). Development of Hypocalcemia Due to Targeted Therapies. Turkish Journal of Endocrinology and Metabolism, Cilt: 24 - Sayı: 1, 105–108. https://ajindex.com/articles/370659

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Kaynakça (9)

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