Dergiler / Turkish Journal of Cancer / 1999 / Cilt: 29 - Sayı: 2

Correlation of flow cytometric parameters with gallium-67 scintigraphic images in lymphoma patients

Sayfa
65–73
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Since both flow cytometry and Gallium-67 tumour scintigraphy reflect the biological activity of the tumour tissue in lymphoma patients, the results of this study suggest both methods may have a significant role in further follow-up and treatment.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The purpose of this study was to correlate the findings between flow cytometric parameters and Gallium-67 scintigraphic imaging results in Hodgkin's and non-Hodgkin's lymphoma patients.
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Temel Bulgular & Veri:DNA content and cell cycle analysis were performed and cytometric parameters were obtained in 24 patients aged between 16-62.
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Sonuç & Katkı:Since both flow cytometry and Gallium-67 tumour scintigraphy reflect the biological activity of the tumour tissue in lymphoma patients, the results of this study suggest both methods may have a significant role in further follow-up and treatment.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Radyonüklid görüntüleme · Lenfom · Lenfom

Abstract

The purpose of this study was to correlate the findings between flow cytometric parameters and Gallium-67 scintigraphic imaging results in Hodgkin's and non-Hodgkin's lymphoma patients. DNA content and cell cycle analysis were performed and cytometric parameters were obtained in 24 patients aged between 16-62. Planar and SPECT images were obtained using Gallium-67. The results were correlated with CT and/or MRI. When scintigraphic studies and flow cytometry results were analyzed together, there was a significant relation between S phase fraction and Gallium-67 imaging findings (p:0.005, r:0.054, Spearman test). While an inverse relation was present between Gallium-67 studies and G1 phase values (p:0.005; r:0.054, Spearman test), no relation was found for G2+M phase (p:0.053; r:0.39, Spearman test). Since both flow cytometry and Gallium-67 tumour scintigraphy reflect the biological activity of the tumour tissue in lymphoma patients, the results of this study suggest both methods may have a significant role in further follow-up and treatment.

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Bu Makaleye Atıf Yap

KIRATLI, Ö. P., CANPINAR, H., KOSTAKOĞLU, L., RUACAN, Ş., KANSU, E. (1999). Correlation of flow cytometric parameters with gallium-67 scintigraphic images in lymphoma patients. Turkish Journal of Cancer, Cilt: 29 - Sayı: 2, 65–73. https://ajindex.com/articles/368418