Dergiler / The Anatolian Journal of Cardiology / 2016 / Cilt: 16 - Sayı: 3

Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women

Sayfa
202–209
DOI
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We found a sensitivity of 64.3% and specificity of 82.9% by receiver operating characteristic [ROC; area under the ROC curve (AUC=0.759)] in the prediction of AAC by ?BMD.Conclusion: This AP subtracting BMD DXA method provides a useful tool for detecting and scoring subclinical and extensive AAC in postmenopausal women using a simple, semiquantitative, and accurate scoring system with minimal radiation exposure and low cost

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Osteoporosis and abdominal aortic calcification (AAC) are associated with increased morbidity and mortality in postmenopausal women.
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Temel Bulgular & Veri:The aim of this study was to determine the accuracy of anterior-posterior (AP) dual-energy X-ray absorptiometry (DXA) compared with that of X-ray lateral lumbar radiography (LLR) in detecting and scoring AAC.Methods: In this cross-sectional study conducted in 56 postmenopausal asymptomatic females aged 59.0±9.3 years and who never used medications to treat osteoporosis before, we determined femoral neck and lumbar spine bone mineral density (BMD) by AP DXA and AAC by X-ray LLR.
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Sonuç & Katkı:We found a sensitivity of 64.3% and specificity of 82.9% by receiver operating characteristic [ROC; area under the ROC curve (AUC=0.759)] in the prediction of AAC by ?BMD.Conclusion: This AP subtracting BMD DXA method provides a useful tool for detecting and scoring subclinical and extensive AAC in postmenopausal women using a simple, semiquantitative, and accurate scoring system with minimal radiation exposure and low cost
🔬Tür:Araştırma Makalesi
📍Kapsam:2019 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Osteoporosis and abdominal aortic calcification (AAC) are associated with increased morbidity and mortality in postmenopausal women. The aim of this study was to determine the accuracy of anterior-posterior (AP) dual-energy X-ray absorptiometry (DXA) compared with that of X-ray lateral lumbar radiography (LLR) in detecting and scoring AAC.Methods: In this cross-sectional study conducted in 56 postmenopausal asymptomatic females aged 59.0±9.3 years and who never used medications to treat osteoporosis before, we determined femoral neck and lumbar spine bone mineral density (BMD) by AP DXA and AAC by X-ray LLR. We hypothesized that the subtracted femoral neck BMD (BMDBMD FN would have a diagnostic value in detecting abdominal vascular calcification.Results: The mean BMDFN was 0.744±0.184 g/cm2, and the mean BMDLS was 0.833±0.157 g/cm2 (p<0.0001); the mean ?BMD was 0.089±0.077 g/cm2, and the mean AAC score was 2.182±1.982. Bivariate Pearson's correlation analysis revealed a significant positive correlation between AAC and ?BMD (r=0.449, p=0.0006); by linear regression analysis, R2=0.2019, and by multiple regression analysis, ?st=13.5244 (p<0.0001). We found a sensitivity of 64.3% and specificity of 82.9% by receiver operating characteristic [ROC; area under the ROC curve (AUC=0.759)] in the prediction of AAC by ?BMD.Conclusion: This AP subtracting BMD DXA method provides a useful tool for detecting and scoring subclinical and extensive AAC in postmenopausal women using a simple, semiquantitative, and accurate scoring system with minimal radiation exposure and low cost

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Bu Makaleye Atıf Yap

AVRAMOVSKI, P., AVRAMOVSKA, M., LAZAREVSKİ, M., SİKOLE, A. (2016). Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women. The Anatolian Journal of Cardiology, Cilt: 16 - Sayı: 3, 202–209. https://ajindex.com/articles/365857

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Kaynakça (13)

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