Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightLikewise, at 2-year follow-up, MACE did not differ between the groups (23.2% vs. 27.5%, RR 1.2, 95% CI0.6-1.5, p=0.408).Conclusion: DCB length was not associated with clinical outcome during a 2-year follow-up period.
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Özet
Objective: In-stent restenosis (ISR) is a feared complication after coronary stent implantation. Drug-coated balloon (DCB) is being promoted asa treatment option for ISR. However, the benefit-risk ratio of DCB length has not been investigated. Longer DCBs release more anti-proliferativedrug to the vessel wall; however, they are associated with a higher lesion length and vessel injury. Hypothesis: DCB length is associated withclinical outcome.Methods: We analyzed 286 consecutive Pantera Lux (Biotronik, active component Paclitaxel) DCB-treated patients between April 2009 and June2012. Of them, 176 patients were treated using a 15-mm DCB and 109 were treated using a 20-mm DCB. Baseline characteristics and major adversecardiac events (MACE; death, myocardial infarction, and target lesion revascularization) during initial hospital stay and a 2-year follow-upperiod were obtained.Results: Patients characteristics such as cardiovascular risk factors, prior diseases, co-medication, clinical presentation, target vessel, andleft ventricular function did not differ between the groups. MACE during hospital course was similar [1.7% vs. 2.8%, relative risk (RR) 1.6, 95%confidence interval (CI) 0.3-7.9, p=0.554]. Likewise, at 2-year follow-up, MACE did not differ between the groups (23.2% vs. 27.5%, RR 1.2, 95% CI0.6-1.5, p=0.408).Conclusion: DCB length was not associated with clinical outcome during a 2-year follow-up period.