Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightThe cut-off value determined for the neutrophil-to-lymphocyte ratio (NLR) was 2.33 and it was an effective value in survival analysis (p<0.05).Conclusion: Surgical treatment should be considered for early GC patients with high-grade tumors and cases demonstrating LVI.The overall survival was shorter in patients with a high NLR value and LNM.
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Özet
Objectives: Selected patients with early gastric cancer (GC) are treated endoscopically. Lymph node metastasis (LNM) in the T1stage may also be detected during surgical resection for early GC. The aim of this study was to determine factors associated withLNM and the effect on survival.Methods: A total of 63 patients with tumor invasion stage T1a or T1b who were operated on for early GC between 2010 and 2018were included in the study. Parameters were investigated retrospectively to identify predictive factors for LNM and overall survival.Significance was defined with a 2-sided p-value of <0.05.Results: Among the 63 patients, 21 (33.3%) had LNM. Lymphovascular invasion (LVI) (p=0.02) and a high-grade tumor (p=0.02)were significantly associated with LNM. The overall survival rate was 73.0%. The number of patients with LNM was greater amongthe deceased patients compared with the censored group (p=0.03). The median follow-up time of the entire group was 28 months(range: 12-55 months) while it was 23 months (range: 7-39 months) in the deceased group and 33.5 months (15.5-60 months) inthe censored group (p=0.06). The mean survival was 62.36 months in patients with LNM and 71.99 months in those without LNM(p=0.09). The cut-off value determined for the neutrophil-to-lymphocyte ratio (NLR) was 2.33 and it was an effective value in survival analysis (p<0.05).Conclusion: Surgical treatment should be considered for early GC patients with high-grade tumors and cases demonstrating LVI.The overall survival was shorter in patients with a high NLR value and LNM.