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Dergiler / Şişli Etfal Hastanesi Tıp Bülteni / 2020 / Cilt: 54 - Sayı: 1

Oncocytic Lesions of Salivary Glands with Morphological and Immunohistochemical Findings

Seyhan ÖZAKKOYUNLU HASÇİÇEK
Deniz TUNCEL
Özlem ÜNSAL
Fevziye KABUKCUOĞLU
Sayfa
88–93
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We present histochemical andimmunohistochemical findings of these lesions in light of the literature.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Salivary gland neoplasms are less than 5% of all head and neck neoplasms (1).
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Temel Bulgular & Veri:According to the WorldHealth Organization (WHO), 4th Head and Neck Tumours Classification oncocytic salivary gland lesions are classified as nodular oncocytic hyperplasia, oncocytoma and oncocytic carcinoma.
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Sonuç & Katkı:We present histochemical andimmunohistochemical findings of these lesions in light of the literature.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016-2017 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: Salivary gland neoplasms are less than 5% of all head and neck neoplasms (1). Although there are morphological similarities between different neoplasms, there may be catchy morphological differences in a single tumour. According to the WorldHealth Organization (WHO), 4th Head and Neck Tumours Classification oncocytic salivary gland lesions are classified as nodular oncocytic hyperplasia, oncocytoma and oncocytic carcinoma. Oncocytic cells may be a component of other salivary gland neoplasmsand metastatic malignities.Methods: In this study, salivary gland oncocytic lesions diagnosed in 2016-2017 were evaluated with Haematoxylin and Eosin(H&E) sections and PAS, diastase resistance PAS, p63, DOG1, cytokeratin7 (CK7), androgen receptor (AR) and PAX8 stains.Results: Nineteen cases were benign, two cases were malignant. Eighteen of the benign lesions were Warthin tumour (WT), onecase was oncocytoma with nodular oncocytic hyperplasia. Acinic cell carcinoma (AciCCA) with oncocytic cells predominant wasone of the malignant cases. The other case was high-grade salivary duct carcinoma (SDCA).Conclusion: The rarity and heterogeneity of this group of lesions may cause difficulties in diagnosis. We present histochemical andimmunohistochemical findings of these lesions in light of the literature.

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Bu Makaleye Atıf Yap

HASÇİÇEK, S. Ö., TUNCEL, D., ÜNSAL, Ö., KABUKCUOĞLU, F. (2020). Oncocytic Lesions of Salivary Glands with Morphological and Immunohistochemical Findings. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 54 - Sayı: 1, 88–93. https://ajindex.com/articles/363723

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Kaynakça (14)

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