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AI InsightPANDAS should be considered in children with neuropsychiatric disorders, especially symptomsassociated with infection periods.
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Özet
Paediatric autoimmune neuropsychiatric disorders associated with streptococci (PANDAS) are important neuropsychiatric disorders in childhood. Streptococcus pyogenes infection associated with tics, obsessive-compulsive disorders, and chorea co-occurrence is important. Swedo et al. have increased the awareness of this situation since 1998. How streptococcal infections give rise tothis condition is not clear yet, but the severity of the symptoms is reduced by the treatment of streptococcal infections is important.Eight-year- nine-month-old girl presented with complaints of a 2-year history of upper respiratory tract infections and increasedseverity of blinking of eyes, throat cleaning, tic disorder and obsession with hand cleaning. In addition, choreiform movementswere present and fluoxetine did not improve the symptoms. The patient was followed-up and treated with PANDAS pre-diagnosis.Streptococcus treatment and prophylaxis decreased the patient’s complaints.A six-year-four months old boy, admitted with abnormal hand and body movements, which increased severity after the schoolperiod, and causing deteriorated fine motor skills during infectious periods for two years. There were also complaints with vocaltics and obsessive-compulsive disorder in the form of throat cleaning. Treatment of S. pyogenes was administered in throat culture.After the penicillin prophylaxis, the complaints decreased.In this study, two patients were presented with choreiform movements, obsessive-compulsive disorder and tic disorder due tofollow-up PANDAS diagnosis. PANDAS should be considered in children with neuropsychiatric disorders, especially symptomsassociated with infection periods.