Dergiler / Şişli Etfal Hastanesi Tıp Bülteni / 2021 / Cilt: 55 - Sayı: 3

Does Pulmonary Hamartoma Increase the Risk of Lung Cancer? Outcomes of 38 Pulmonary Hamartoma Cases

Sayfa
344–348
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Hamartomas may be associated with lung cancer at the time of diagnosis or follow-up, so it should be kept in mind that a different nodule seen in patients diagnosed with hamartoma may be associated with lung cancer.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objectives: Hamartomas are common benign tumors of the lung.
📊
Temel Bulgular & Veri:Methods: Between 2016 and 2019, 38 patients who underwent a surgical procedure and diagnosed with lung hamartoma were retrospectively evaluated regarding clinicopathological features.
💡
Sonuç & Katkı:Hamartomas may be associated with lung cancer at the time of diagnosis or follow-up, so it should be kept in mind that a different nodule seen in patients diagnosed with hamartoma may be associated with lung cancer.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: Hamartomas are common benign tumors of the lung. Rarely, lung cancer coincidence may occur at the time of diagnosis or in the follow-up period. Methods: Between 2016 and 2019, 38 patients who underwent a surgical procedure and diagnosed with lung hamartoma were retrospectively evaluated regarding clinicopathological features. Cases were analyzed according to age, sex, radiological findings, localization of nodules, surgical methods, and the coincidence of lung cancer. Results: The mean age was 50.2±11.1 (range 28–76 years). There were 23 male (60.5%) and 15 female (39.5%) patients. Mean size was 2.7±1.8 (range 0.8–10 cm). In 28 patients, hamartoma was <3 cm in diameter (73.6%). Eighteen hamartomas were localized in the upper lobe (47.4%). Only 6 cases (15.8%) were localized at the central part of the lung. Multiple nodules were reported in 10 cases (26.3%). In 4 cases (10.5%), lung carcinoma and hamartoma were seen together at the time of diagnosis. Video-assisted thoracoscopic surgery (VATS) has been performed in 29 cases (76.3%). As a surgical method, enucleation was performed in 4 cases (10.5%), wedge resection in 28 cases (73.7%), and lobectomy in 6 cases (15.8%). No post-operative mortality appeared in the early follow-up. Conclusion: Pulmonary hamartomas are usually present as solitary pulmonary nodules with benign radiological findings. VATS wedge resection is a method that can be used safely in diagnosis and treatment. Hamartomas may be associated with lung cancer at the time of diagnosis or follow-up, so it should be kept in mind that a different nodule seen in patients diagnosed with hamartoma may be associated with lung cancer.

🔖

Bu Makaleye Atıf Yap

ERDOĞU, V., DEMİRKOL, E. Y., KUTLUK, A. C., ONAY, S., ÇİFTÇİ, A., BİLEN, S., ERDUHAN, S., YILDIZ, N., AKİN, H., METİN, M. (2021). Does Pulmonary Hamartoma Increase the Risk of Lung Cancer? Outcomes of 38 Pulmonary Hamartoma Cases. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 55 - Sayı: 3, 344–348. https://ajindex.com/articles/363381

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (5)

  1. Shields TW, Robinson PG. Benign tumors of the lung. General Thoracic Surgery 2004;2:1778–81
  2. Okudela K, Umeda S, Otara M, Honda E, Ohmori T, Tajari M, et al. A case of pulmonary hamartoma with distinctive histopathological features: a discussion of its differential diagnosis and histogenesis. Pathol Int 2014;64:618–23. [CrossRef] 3. Narita T, Takahashi H. Unusual cyst adenomatoid hamartoma of the lung. Histopathology 1996;5:285–7. [CrossRef] 4. Khouri NF, Meziane MA, Zerhouni EA, Fishman EK, Siegelman SS. The solitary pulmonary nodule. Assessment, diagnosis, and management. Chest 1987;91:128–33. [CrossRef] 5. Thomas JW, Staerkel GA, Whitman GJ. Pulmonary hamartoma. AJR Am J Roentgenol 1999;172:1643. [CrossRef] 6. Itoga M, Kobayashi Y, Takeda M, Moritoki Y, Tamaki M, Nakazawa K, et al. A case of pulmonary hamartoma showing rapid growth. Case Rep Med 2013;2013:231652. [CrossRef] 7. Şahin C, Yılmaz O, Üçpınar BA, Uçak R, Temel U, Başak M, et al. Computed tomography-guided transthoracic core needle biopsy of lung masses: technique, complications and diagnostic yield rate. Sisli Etfal Hastan Tip Bul 2020;54:47–51. [CrossRef] 8. Goldsworthy NE. Chondroma of lung (hamartoma chondromatosum pulmonis) with report of case. J Pathol Bacteriol 1934;39:291–8. [CrossRef] 9. Wolfgang D. Radiology review manual. 3rd ed. Baltimore: Lippincott Williams & Wilkins; 1996
  3. Tözüm H, Üçvet A, Gürsoy S, Kul C, Şirzai S, Başok O, et al. Hamartoma of the lung: an analysis of 15 cases. Turkish J Thorac Cardiovasc Surg 2009;17:186–90
  4. Hutter J, Reich-Weinberger S, Hutarew G, Stein HJ. Giant pulmonary hamartoma-a rare presentation of a common tumor. Ann Thorac Surg 2006;82:e5–7. [CrossRef] 12. Nicholson AG, Tomashefski Jr JF, Popper H. Hamartoma. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC, editors. World Health Organization Classification of Tumours. Pathology and genetics of tumours of the lung, pleura, thymus and heart. Lyon: IARC Press; 2004. p. 113–4
  5. Kervancioğlu R, Bayram MM, Elbeyli L. Giant pulmonary hamartoma. AJR Am J Roentgenol 1997;168:573. [CrossRef] 14. Erasmus JJ, Connolly JE, McAdams HP, Roggli VL. Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics 2000;20:43–58. [CrossRef] 15. Ettinger DS, Aisner DL, Wood DE, Akerley W, Bauman J, Chang JY, et al. NCCN Guidelines Insights: Non-Small Cell Lung Cancer, version 5.2018. J Natl Compr Canc Netw 2018;16:807–21. [CrossRef