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Dergiler / The Journal of Pediatric Research / 2018 / Cilt: 5 - Sayı: 3

Does Obesity Affect the Ocular Choroid Tissue in Children and Adolescents?

Bediz ÖZEN
Hakan ÖZTÜRK
Gönül ÇATLI
Bumin DÜNDAR
Sayfa
112–117
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Increased adipose tissue may result in a susceptibility to damage by thinningchoroid tissue.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Obesity may cause microangiopathic changes associated with the inflammatory process.
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Temel Bulgular & Veri:The choroid tissue of the eye is one of the most highlyvascularized tissues of body and supplies the outer 1/3 of the retina.
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Sonuç & Katkı:Increased adipose tissue may result in a susceptibility to damage by thinningchoroid tissue.
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Aim: Obesity may cause microangiopathic changes associated with the inflammatory process. The choroid tissue of the eye is one of the most highlyvascularized tissues of body and supplies the outer 1/3 of the retina. Thinning in choroid tissue is an indicator of damage. Few studies have investigatedobesity-induced choroid tissue damage in children, and their findings are inconsistent. The purpose of this study was to investigate changes in choroidtissue thickness in non-diabetic children and adolescents using optic coherence tomography (OCT) and the association with metabolic risk factors.Materials and Methods: One hundred fifty-six eyes of 38 obese and 40 healthy children and adolescents aged 10-18 were included in the study. Thebilateral choroidal thicknesses were measured. We then investigated correlations between choroidal thickness and age, body measurements, pubertalstages, systolic and diastolic blood pressures, homeostasis model assessment insulin resistance and lipid values.Results: Mean choroidal thicknesses measured using OCT were 284.4±34.9 μm in the obese group and 316.3±39.7 μm in the control group (p=0.018).Choroidal thickness in the obese group decreased as body mass index (BMI) standard deviation scores (SDS) increased (r=-0.390, p=0.000).Conclusion: Mean choroidal thickness was lower in obese children and adolescents in this study compared to the healthy controls and thinning inthe choroid tissue was more pronounced as BMI-SDS values increased. Increased adipose tissue may result in a susceptibility to damage by thinningchoroid tissue.

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Bu Makaleye Atıf Yap

ÖZEN, B., ÖZTÜRK, H., ÇATLI, G., DÜNDAR, B. (2018). Does Obesity Affect the Ocular Choroid Tissue in Children and Adolescents?. The Journal of Pediatric Research, Cilt: 5 - Sayı: 3, 112–117. https://ajindex.com/articles/362915

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Kaynakça (14)

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