Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightVeterinary medicine will help to multidisciplinary collaboration to develop effective vaccines and drugs with many years of coronavirus experiences.
📌 3 Maddede Bu Makale
Özet
Feline coronavirus 176 seropositive cats were examined in 2014-2019. Seroepidemiological, serological, clinical, haematological and biochemical data were analysed with IBM-SPSS Statistics. Clinicopathological signs were typical with enteric form in 125 cats (71%) and FIPV in 51 cats (29%). Fever, depression, dullness, weight loss, vomitus, growth retardation, diarrhoea, ocular and neurological symptoms were findings. 40 cats (23%) were died, 17 had pleural effusion, 19 had ascites, and 16 Rivalta tests were positive. Post-mortem FIP confirmation was at 8 cats. Of the FCoV seropositive cats, 22 (12.5%) had FIV antibodies, 7 (3.9%) were positive for FLV antigens, 2 (1.1%) were positive for FCoV, FIV and FLV, and 2 (1.1%) were FmopV RNA positive. FCoV, canine enteric CoV, human CoV-229E and CoV-NL63 belong to Alphacoronavirus, and canine respiratory CoV, Human CoV-OC43, CoV-HKU1, SARS, MERS and COVID-19 belong to Betacoronavirus genus, originated from bat gene pool and is of animal origin cause zoonotic infections. Covid-19 pathogenesis is not fully understood and data‘s focused on case fatality rates. Covid-19 was reported as anthropozoonosis infecting cats, dogs, tigers and lions. The panthropism risk should be investigated. In particular, the clinicopathology and treatment modalities of feline coronavirus and COVID-19 infections are having similarities such as GS-441524 as the main metabolite of remdesivir prodrug and dexamethazone responses, and both can cause resident and persistent infections in many organs, including the eyes and brain, of varying severity. The obtained data have been evaluated in the 'One Health' approach to better understand the aetiology, pathogenesis and clinicopathology of coronavirus infections, and presenting valuable findings to help the control of COVID-19 epidemic. Veterinary medicine will help to multidisciplinary collaboration to develop effective vaccines and drugs with many years of coronavirus experiences.