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Dergiler / BEYOGLU EYE JOURNAL / 2020 / Cilt: 5 - Sayı: 3

Evaluation of Posterior Ocular Structures in Patients with Isolated Iris Coloboma

Serkan AKKAYA
Sayfa
228–233
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Longitudinal studies are required to understand if a thinner LCT in coloboma eyes is associated with any future problems.

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Amaç & Hipotez:Objectives: To measure lamina cribrosa thickness (LCT), lamina cribrosa depth (LCD) and subfoveal choroidal thickness (SFCT) by imaging posterior ocular structures in pediatric cases with isolated unilateral iris coloboma and to investigate the differences as compared with healthy contralateral eyes of these cases (fellow eyes) and healthy control eyes.Methods: This cross-sectional, comparative prospective study included seven children (age range, 9-17 years) with unilateral isolated iris coloboma.
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Temel Bulgular & Veri:An age-matched (age range 8-17 years) control group (n=9), including children with both eyes having either normal or corrected-to-nor-mal visual acuity, was formed.
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Sonuç & Katkı:Longitudinal studies are required to understand if a thinner LCT in coloboma eyes is associated with any future problems.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: To measure lamina cribrosa thickness (LCT), lamina cribrosa depth (LCD) and subfoveal choroidal thickness (SFCT) by imaging posterior ocular structures in pediatric cases with isolated unilateral iris coloboma and to investigate the differences as compared with healthy contralateral eyes of these cases (fellow eyes) and healthy control eyes.Methods: This cross-sectional, comparative prospective study included seven children (age range, 9-17 years) with unilateral isolated iris coloboma. The healthy contralateral eyes of these cases formed the fellow group. An age-matched (age range 8-17 years) control group (n=9), including children with both eyes having either normal or corrected-to-nor-mal visual acuity, was formed. A detailed ophthalmic examination was performed. The posterior ocular segments were evaluated using spectral domain-optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) technique.Results: The SFCT was 372.0±48.8 μm, 375.3±44.0 μm, and 386.5±71.8 μm, respectively, and the LCD was 362.4±68.3 μm, 354.4±47.1 μm, and 350.7±38.1 μm, respectively, in the coloboma, fellow, and control eyes. There was no difference between the groups regarding SFCT and LCD. The mean LCT was significantly thinner in the coloboma eyes (200.2±9.5 μm) than in the fellow (238.8±26.7 μm; p=0.023) and control eyes (240.0±12.9 μm; p<0.001). The LCT showed no signif-icant correlation with age, axial length or spherical equivalent.Conclusion: Better visual prognosis is expected in isolated iris coloboma. However, detailed examinations using new technologies, such as SD-OCT, may reveal some structural changes. Longitudinal studies are required to understand if a thinner LCT in coloboma eyes is associated with any future problems.

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Bu Makaleye Atıf Yap

AKKAYA, S. (2020). Evaluation of Posterior Ocular Structures in Patients with Isolated Iris Coloboma. BEYOGLU EYE JOURNAL, Cilt: 5 - Sayı: 3, 228–233. https://ajindex.com/articles/353074

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Kaynakça (18)

  1. Ohuchi H, Sato K, Habuta M, Fujita H, Bando T. Congenital eye anomalies: more mosaic than thought? Congenit Anom (Kyoto) 2019;59:56–73
  2. Onwochei BC, Simon JW, Bateman JB, Couture KC, Mir E. Ocular colobomata. Surv Ophthalmol 2000;45:175–94
  3. Vogt G, Puhó E, Czeizel AE. A population-based case-control study of isolated ocular coloboma. Ophthalmic Epidemiol 2005;12:191–7
  4. Uhumwangho OM, Jalali S. Chorioretinal coloboma in a paediatric population. Eye (Lond) 2014;28:728–33
  5. Nakamura KM, Diehl NN, Mohney BG. Incidence, ocular findings, and systemic associations of ocular coloboma: a population- based study. Arch Ophthalmol 2011;129:69–74
  6. Gregory-Evans CY, Williams MJ, Halford S, Gregory-Evans K. Ocular coloboma: a reassessment in the age of molecular neuroscience. J Med Genet 2004;41:881–91
  7. Cionni RJ, Karatza EC, Osher RH, Shah M. Surgical technique for congenital iris coloboma repair. J Cataract Refract Surg 2006;32:1913–6
  8. Karatepe Haşhaş AS, Arifoğlu HB, Yüce Y, Duru N, Ulusoy DM, Zararsız G. Evaluations of corneas in eyes with isolated iris coloboma. Curr Eye Res 2017;42:41–6
  9. Hornby SJ, Adolph S, Gilbert CE, Dandona L, Foster A. Visual acuity in children with coloboma: clinical features and a new phenotypic classification system. Ophthalmology 2000;107:511–20
  10. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol 2008;146:496–500
  11. Park SC, Ritch R. High resolution in vivo imaging of the lamina cribrosa. Saudi J Ophthalmol 2011;25:363–72
  12. Adhi M, Duker JS. Optical coherence tomography-current and future applications. Curr Opin Ophthalmol 2013;24:213–21
  13. Lee EJ, Kim TW, Weinreb RN, Park KH, Kim SH, Kim DM. Visualization of the lamina cribrosa using enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol 2011;152:87-95.e1
  14. Nuyen B, Mansouri K, Weinreb RN. Imaging of the lamina cribrosa using swept-source optical coherence tomography. J Curr Glaucoma Pract 2012;6:113–9
  15. Park SC. In vivo evaluation of lamina cribrosa deformation in glaucoma. J Glaucoma 2013;22 (Suppl 5):S29–31
  16. Quigley HA. The contribution of the sclera and lamina cribrosa to the pathogenesis of glaucoma: Diagnostic and treatment implications. Prog Brain Res 2015;220:59–86
  17. Abe RY, Gracitelli CPB, Diniz-Filho A, Tatham AJ, Medeiros FA. Lamina Cribrosa in glaucoma: diagnosis and monitoring. Curr Ophthalmol Rep 2015;3:74–84
  18. Sigal IA, Wang