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Dergiler / BEYOGLU EYE JOURNAL / 2021 / Cilt: 6 - Sayı: 1

Effects of Topical Carbonic Anhydrase Inhibitors on the Olfactory Sense

Fatih Cem GÜL
Mete GÜLER
Sabiha GÜNGÖR KOBAT
Sertaç DÜZER
Öner SAKALLIOĞLU
Fatih ÇELİK
Abdulvahap AKYİĞİT
Sayfa
19–23
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Sniffin’ Sticks (Burghart Messtechnik GmbH, Wedel, Germany) were used to evaluate patient olfactory sensitivity before starting the topical treatment and after 1 week of treatment.Results: No statistically significant decrease in olfactory performance was observed in users of either brinzolamide or dorzolamide (p=0.705, p=0.405 respectively).Conclusion: No negative effect on the sense of smell was determined after 7 days of topical application of a carbonic anhydrase enzyme inhibitor to the eye in patients with no previous anosmia.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: The sense of smell plays an important role in daily life.
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Temel Bulgular & Veri:Olfactory impairment can significantly affect an individual’s quality of life.
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Sonuç & Katkı:Sniffin’ Sticks (Burghart Messtechnik GmbH, Wedel, Germany) were used to evaluate patient olfactory sensitivity before starting the topical treatment and after 1 week of treatment.Results: No statistically significant decrease in olfactory performance was observed in users of either brinzolamide or dorzolamide (p=0.705, p=0.405 respectively).Conclusion: No negative effect on the sense of smell was determined after 7 days of topical application of a carbonic anhydrase enzyme inhibitor to the eye in patients with no previous anosmia.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: The sense of smell plays an important role in daily life. Olfactory impairment can significantly affect an individual’s quality of life. Topical carbonic anhydrase inhibitors are commonly used to treat elevated intraocular pressure(IOP). One potential side effect of these drugs is a loss of the sense of smell. This study is an examination of changes in olfactory function in patients who used dorzolamide and brinzolamide to control IOP after a laser capsulotomy.Methods: A total of 60 patients with posterior capsule opacification were included in the study. Sniffin’ Sticks (Burghart Messtechnik GmbH, Wedel, Germany) were used to evaluate patient olfactory sensitivity before starting the topical treatment and after 1 week of treatment.Results: No statistically significant decrease in olfactory performance was observed in users of either brinzolamide or dorzolamide (p=0.705, p=0.405 respectively).Conclusion: No negative effect on the sense of smell was determined after 7 days of topical application of a carbonic anhydrase enzyme inhibitor to the eye in patients with no previous anosmia.

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Bu Makaleye Atıf Yap

GÜL, F. C., GÜLER, M., KOBAT, S. G., DÜZER, S., SAKALLIOĞLU, Ö., ÇELİK, F., AKYİĞİT, A. (2021). Effects of Topical Carbonic Anhydrase Inhibitors on the Olfactory Sense. BEYOGLU EYE JOURNAL, Cilt: 6 - Sayı: 1, 19–23. https://ajindex.com/articles/353066

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