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Dergiler / BEYOGLU EYE JOURNAL / 2020 / Cilt: 5 - Sayı: 3

Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy

Alper BAYAT
Akin CAKİR
Mustafa ELCİOĞLU
Diğdem BEZEN
Sayfa
174–177
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

SD-OCT can reveal neurodegenerative changes that may occur before vascular changes in diabetic children.

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Amaç & Hipotez:Objectives: This study is an analysis of the subfoveal choroidal thickness (SFCT) and ganglion cell complex (GCC) in children who have type 1 diabetes mellitus (T1D) without diabetic retinopathy.Methods: In all, 36 right eyes of 36 patients with T1D and 36 right eyes of sex- and age-matched healthy subjects were included in this prospective study.
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Temel Bulgular & Veri:Correlations between SCFT, GCC and duration of T1D, glycated hemoglobin, and age were also investigated.Results: The mean SFCT was 342.1±42.3 μm in the T1D group and 354±70.8 μm in the control group (p>0.05).
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Sonuç & Katkı:SD-OCT can reveal neurodegenerative changes that may occur before vascular changes in diabetic children.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: This study is an analysis of the subfoveal choroidal thickness (SFCT) and ganglion cell complex (GCC) in children who have type 1 diabetes mellitus (T1D) without diabetic retinopathy.Methods: In all, 36 right eyes of 36 patients with T1D and 36 right eyes of sex- and age-matched healthy subjects were included in this prospective study. SFCT and GCC measurements were obtained using spectral domain optical coherence tomography (SD-OCT). Correlations between SCFT, GCC and duration of T1D, glycated hemoglobin, and age were also investigated.Results: The mean SFCT was 342.1±42.3 μm in the T1D group and 354±70.8 μm in the control group (p>0.05). There was no significant difference between the groups in the GCC superior and inferior retina values. The average GCC was thinner in the T1D group (T1D group: 88.11±14.93 μm, control group: 103.39±15.65 μm; p=0.005). The mean central retinal thickness (CRT) was decreased in the T1D group (T1D group: 248.1±16.5 μm, control group: 262.1±18.3 μm; p=0.021).Conclusion: The mean SFCT was not significantly different in diabetic children compared with healthy eyes. The CRT and average GCC thickness were lower in children with T1D. SD-OCT can reveal neurodegenerative changes that may occur before vascular changes in diabetic children.

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Bu Makaleye Atıf Yap

BAYAT, A., CAKİR, A., ELCİOĞLU, M., BEZEN, D. (2020). Subfoveal Choroidal Thickness and Ganglion Cell Complex in Children with Type 1 Diabetes Mellitus Without Diabetic Retinopathy. BEYOGLU EYE JOURNAL, Cilt: 5 - Sayı: 3, 174–177. https://ajindex.com/articles/352475

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