Dergiler / Bağcılar Tıp Bülteni / 2021 / Cilt: 6 - Sayı: 2

Comparison of the Effect of Different Anesthesia Maintenance on Hemodynamics in Coronary Artery Bypass Grafting Surgery: A Retrospective Cohort Study

Koroner Arter Baypas Greftleme Cerrahisinde Farklı Anestezi İdamesinin Hemodinami Üzerine Etkisinin Karşılaştırılması: Retrospektif Bir Kohort Çalışması

Sayfa
105–111
DOI
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There was not change more than 20-25% in MAP and HR in group I than the others.Conclusion: Better hemodynamic results were achived with sevoflurane and fentanyl in the anesthetic maintenance of CABGC.

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Amaç & Hipotez:Objective: General anesthesia management in coronary artery bypass graft surgery (CABGC) should preserve myocardial function, prevent ischemic damage, and maintain stable hemodynamics.
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Temel Bulgular & Veri:Drugs or drug combinations and maintenance of infusions are decided based on the pathophysiological condition of the patient and the individual preference and experience of the anesthesiologist (1).
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Sonuç & Katkı:There was not change more than 20-25% in MAP and HR in group I than the others.Conclusion: Better hemodynamic results were achived with sevoflurane and fentanyl in the anesthetic maintenance of CABGC.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: General anesthesia management in coronary artery bypass graft surgery (CABGC) should preserve myocardial function, prevent ischemic damage, and maintain stable hemodynamics. There is not a universally accepted technique for anesthetic management during CABGC. Drugs or drug combinations and maintenance of infusions are decided based on the pathophysiological condition of the patient and the individual preference and experience of the anesthesiologist (1). Although there are many studies about an anesthesia induction in CABGC, studies about anesthetic maintenance are very limited. In this study, we compared the hemodynamic effects of three different methods that were used in anesthetic maintenance in CABGC.Method: The retrospective records of 108 patients in ASA II-III group who underwent elective CABGC were divided into 3 groups according to their anesthetic maintenance methods. Group I was maintained with 1-3% sevoflurane and fentanyl 4 mcg/kg/hour infusion, group II with propofol 1.5-4 mg/kg/hour and fentanyl 4 mcg/kg/hour infusion, and group III with propofol 1.5-4 mg/kg/hour and remifentanil infusion of 0.03 mg/kg/hour. Systolic blood pressure, diastolic blood pressure, mean arterial pressure (MAP) and heart rate (HR) were measured and recorded after induction (T0), after sternotomy (T1), after pericardiotomy (T2), 5 minutes after cardiopulmonary bypass (CPB) (T3), after thorax closure (T4), at the end of the operation (T5). The vasodilator requirements in the time period before CBP and the inotropic agent requirements after CPB were noted.Results: Data of 108 patients (88 men/20 women) were analyzed. Demographic characteristics of the patients were similar in all the groups. Statistical analysis was made among the groups depending on coronary artery bypass graft number, cross-clamp time, total fluid administration, total blood transfusion, total urine volume, inotropic agent requirement after CPB, postoperative central venous pressure, and pre- and postoperative lactate levels; however, there was no statistical difference. There was not change more than 20-25% in MAP and HR in group I than the others.Conclusion: Better hemodynamic results were achived with sevoflurane and fentanyl in the anesthetic maintenance of CABGC.

Abstract

Amaç: Koroner arter baypas greft cerrahisinde (KABGC) genel anestezi yönetimi miyokard fonksiyonunu korumalı, iskemik hasarı önlemeli ve stabil hemodinamiyi sağlamalıdır. KABGC sırasında anestezi yönetimi için evrensel olarak kabul edilmiş olan tek bir teknik bulunmamaktadır. Kullanılan ilaçlar ve ilaç kombinasyonları, idame infüzyonları hastanın patofizyolojik durumu ile anesteziyoloji ve reanimasyon uzmanının bireysel tercihi ile deneyimine dayanır. KABGC’sinde anestezi indüksiyonu ile ilgili çok sayıda çalışma olsa da anestezi idamesi ile ilgili çalışmalar kısıtlıdır. Bu çalışmada, retrospektif olarak KABGC’sinde anestezi idamesinde kullanılmış 3 farklı yöntemin hemodinami üzerine etkileri karşılaştırıldı. Yöntem: Elektif KABGC uygulanmış olan ASA II-III grubu 108 hastanın kayıtları anestezi idame yöntemlerine göre 3 gruba ayrılmıştır. Grup 1 %1-3 sevofluran ve fentanil 4 mcg/kg/saat infüzyonu, grup 2 propofol 1,5-4 mg/kg/saat ve fentanil 4 mcg/kg/saat infüzyonu, grup 3 propofol 1,5-4 mg/kg/saat ve remifentanil 0,03 mg/kg/saat infüzyonu ile idame edilmişti. İndüksiyon sonrası (T0), sternotomi sonrası (T1), perikardiyotomi sonrası (T2), CPB sonrası beşinci dakikada (T3), toraks kapatılırken (T4) ve operasyon bitiminde (T5) olmak üzere sistolik kan basıncı (SKB), diyastolik kan basıncı, ortalama arter basıncı (OAB), kalp hızı (nabız) kaydedilmişti. Kardiyopulmoner baypas (KBP) öncesi dönemde kullanılan vazodilatatör ilaç ihtiyacı ile KPB sonrasında kullanılmış olan inotropik ajan miktarları hesaplandı. Bulgular: Yüz sekiz hastadan (88 erkek/20 kadın) elde edilen veriler analiz edildi. Hastaların demografik özellikleri her üç grupta da benzerdi. Koroner arter baypas greft sayısı, kros klemp süresi, toplam sıvı, toplam kan transfüzyonu, toplam idrar hacmi, KPB sonrası inotropik ajan gereksinimi, ameliyat sonrası santral venöz basınç, ameliyat öncesi ve sonrası laktat ve laktat artışı açısından gruplar arasında istatistiksel olarak fark yoktu. Grup 1’de diğer gruplara göre, OAB ve nabızda %20-25’ten fazla değişiklik yoktu. Sonuç: KABGC’de sevofluran ve fentanil ile anestezi idamesi daha stabil hemodinami sağladı.

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Bu Makaleye Atıf Yap

AK, H. Y., ÖZŞAHİN, Y., YEŞİLTAŞ, M. A., HABERAL, İ., YILDIZ, M., SALİHOĞLU, Z., ERKALP, K. (2021). Comparison of the Effect of Different Anesthesia Maintenance on Hemodynamics in Coronary Artery Bypass Grafting Surgery: A Retrospective Cohort Study. Bağcılar Tıp Bülteni, Cilt: 6 - Sayı: 2, 105–111. https://ajindex.com/articles/351081

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Kaynakça (12)

  1. Gumus F, Erkalp K, Kayalar N, Alagol A. Cardiac surgery and anesthesia approach in an elderly patient population. Turk Gogus Kalp Dama 2013;21(1):250-255
  2. Kurowicki A, Borys M, Zurek S, Horeczy B, Gaweda B, Belina B, et al. Remifentanil and sevoflurane based anesthesia combined with bilateral erector spinae plane block in patients undergoing offpump coronary artery bypass graft surgery. Videosurgery Miniinv 2020;15(2):346-350
  3. Williams JB, McConnell G, Allender JE, Woltz P, Kane K, Smith PK, et al. One-year results from the first US-based enhanced recovery after cardiac surgery (ERAS Cardiac) program. J Thorac Cardiovasc Surg 2019;157(5):1881-1888
  4. Kwanten LE, O’Brien B, Anwar S. Opioid-based anesthesia and analgesia for adult cardiac surgery: History and narrative review of the literature. J Cardiothorac Vasc Anesth 2019;33(3):808- 816
  5. Landoni G, Guarracino F, Cariello C, Franco A, Baldassarri R, Borghi G, et al. Volatile compared with total intravenous anaesthesia in patients undergoing high-risk cardiac surgery: a randomized multicentre study. Br J Anaest 2014;113(6):955-963
  6. Hillis LD, Smith PK, Anderson JL, Anderson JL, Bittl JA, Bridges CR, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124(23):2610-2642
  7. Abrams J. Nitroglycerin and long-acting nitrates. N Engl J Med 1980;302(22):1234-1237
  8. Lell W, Johnson P, Plagenhoef J, Samuelson P, Athanasuleas C, Hughes W, et al. The effect of prophylactic nitroglycerin infusion on the incidence of regional wall‐motion abnormalities and ST segment changes in patients undergoing coronary artery bypass surgery. J Card Surg 1993;8(Suppl 2):228-231
  9. Hoshijima H, Denawa Y, Mihara T, Takeuchi R, Kuratani N, Mieda T, et al. Efficacy of prophylactic doses of intravenous nitroglycerin in preventing myocardial ischemia under general anesthesia: A systematic review and meta-analysis with trial sequential analysis. J Clin Anesth 2017;40:16-22
  10. Zakhary WZA, Turton EW, Forner AF, von Aspern K, Borger MA, Ender JK. A comparison of sufentanil vs. remifentanil in fast‐track cardiac surgery patients. Anaesthesia 2019;74(5):602-608
  11. Sebel PS, Hoke JF, Westmoreland C, Hug CC Jr, Muir KT, Szlam F. Histamine concentrations and hemodynamic responses after remifentanil. Anesth Analg 1995;80(5):990-993
  12. Lehmann A, Zeit