This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Abnormal metabolism is a key tumor hallmark.
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Temel Bulgular & Veri:Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes.
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Sonuç & Katkı:This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
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Bu Makaleye Atıf Yap
FIGUEIRAS, R. G., GONZALEZ, S. B., PADHANI, R. A., OLEAGA, L., VİLANOVA, J. C., LUNA, A., GOMEZ, J. C. C. (2016). Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?. Diagnostic and Interventional Radiology, Cilt: 22 - Sayı: 1, 75–89. https://ajindex.com/articles/350113
Hajek M, Dezortova M. Introduction to clinical in vivo MR spectroscopy. Eur J Radiol 2008
[CrossRef] Glunde K, Bhujwalla ZM. Metabolic tumor im- aging using magnetic resonance spectroscopy. Semin Oncol 2011
[CrossRef] Glunde K, Bhujwalla ZM, Ronen SM. Choline metabolism in malignant transformation. Nat Rev Cancer 2011
[CrossRef] Kwock L, Smith JK, Castillo M, et al. Clinical role of proton magnetic resonance spectroscopy in oncology: brain, breast, and prostate cancer. Lancet Oncol 2006
[CrossRef] Jansen JF, Carlson DL, Lu Y, et al. Correlation of a prior DCE-MRI and (1)H-MRS data with molecu- lar markers in neck nodal metastases: Initial anal- ysis. Oral Oncol 2012
[CrossRef] Yeung DK, Yang WT, Tse GM. Breast cancer: in vivo proton MR spectroscopy in the characteri- zation of histopathologic subtypes and prelim- inary observations in axillary node metastases. Radiology 2002
[CrossRef] Skoch A, Jiru F, Bunke J. Spectroscopic imaging: basic principles. Eur J Radiol 2008
[CrossRef] Klose U. Measurement sequences for single voxel proton MR spectroscopy. Eur J Radiol 2008
[CrossRef] Pinker K, Stadlbauer A, Bogner W, Gruber S, Helbich TH. Molecular imaging of cancer: MR spectroscopy and beyond. Eur J Radiol 2012
[CrossRef] Posse S, Otazo R, Dager SR, Alger J. MR spectro- scopic imaging: principles and recent advanc- es. J Magn Reson Imaging 2013
[CrossRef] Poullet J-B, Sima DM, Van Huffel S. MRS signal quantitation: A review of time- and frequen- cy-domain methods. J Magn Reson 2008
[CrossRef] Mandal PK. In vivo proton magnetic resonance spectroscopic signal processing for the abso- lute quantitation of brain metabolites. Eur J Radiol 2012
e653-e664. [CrossRef] Bulik M, Jancalek R, Vanicek J, Skoch A, Mechl M. Potential of MR spectroscopy for assess- ment of glioma grading. Clin Neurol Neurosurg 2013
[CrossRef] Horská A, Barker PB. Imaging of brain tumors: MR spectroscopy and metabolic imaging. Neuroim- aging Clin N Am 2010
[CrossRef] McKnight TR. Proton magnetic resonance spec- troscopic evaluation of brain tumor metabolism. Semin Oncol 2004
[CrossRef] Oz G, Alger JR, Barker PB, et al. Clinical pro- ton MR spectroscopy in central nervous sys- tem disorders. Radiology 2014
[CrossRef] Griffin JL, Bollard M, Nicholson JK, et al: Spec- tral profiles of cultured neur