KaydedilenlerDerginizi ekleyin

Dergiler / Dicle Tıp Dergisi / 2011 / Cilt: 38 - Sayı: 4

Metisilin dirençli Staphylococcus aureus suşlarının antibiyotiklere in-vitro duyarlılıkları

In-vitro susceptibility of methicillin-resistant Staphylococcus aureus strains to antibiotics

İsmail GÜLER
Hüseyin KILIÇ
M. Altay ATALAY
DUYGU PERÇİN RENDERS
Barış Derya ERÇAL
Sayfa
466–470
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

On the other hand, TMP-SXT seems to be alternative agent for treatment of MRSA infections.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objectives: Methicillin resistance of S.aureus strains sourced from hospitals and community-acquired has been increasing.
📊
Temel Bulgular & Veri:The aim of this cross-sectional study is to determine the resistance rates to alternative antibiotics of meticilline resistant S.aureus (MRSA) strains, where the multiple resistances are encountered the most.
💡
Sonuç & Katkı:On the other hand, TMP-SXT seems to be alternative agent for treatment of MRSA infections.
🔬Tür:Araştırma Makalesi
📍Kapsam:2008 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: Methicillin resistance of S.aureus strains sourced from hospitals and community-acquired has been increasing. The aim of this cross-sectional study is to determine the resistance rates to alternative antibiotics of meticilline resistant S.aureus (MRSA) strains, where the multiple resistances are encountered the most. Materials and methods: A total of 100 MRSA strains isolated consequently from the clinical samples of hospitalized patients in Erciyes University Medical Faculty Hospitals between September 2008 and October 2009 were included in the study. According to “Clinical and Laboratory Standards Institude (CLSI)” criteria, antimicrobial susceptibility testing was performed by Kirby-Bauer disk diffusion method. Results: The rates of resistance to antibiotics of the MRSA strains included within the study were 77% to erythromycin, 1% to trimethoprim/sulfamethoxazole (TMP-SXT), 90% to rifampin, 63% clindamycin, 84% to gentamicin and 0% to teicoplanin and vancomycin. Conclusion: All MRSA strains were susceptible to vancomycine and teicoplanin. On the other hand, TMP-SXT seems to be alternative agent for treatment of MRSA infections.

Abstract

Objectives: Methicillin resistance of S.aureus strains sourced from hospitals and community-acquired has been increasing. The aim of this cross-sectional study is to determine the resistance rates to alternative antibiotics of meticilline resistant S.aureus (MRSA) strains, where the multiple resistances are encountered the most. Materials and methods: A total of 100 MRSA strains isolated consequently from the clinical samples of hospitalized patients in Erciyes University Medical Faculty Hospitals between September 2008 and October 2009 were included in the study. According to “Clinical and Laboratory Standards Institude (CLSI)” criteria, antimicrobial susceptibility testing was performed by Kirby-Bauer disk diffusion method. Results: The rates of resistance to antibiotics of the MRSA strains included within the study were 77% to erythromycin, 1% to trimethoprim/sulfamethoxazole (TMP-SXT), 90% to rifampin, 63% clindamycin, 84% to gentamicin and 0% to teicoplanin and vancomycin. Conclusion: All MRSA strains were susceptible to vancomycine and teicoplanin. On the other hand, TMP-SXT seems to be alternative agent for treatment of MRSA infections.

🔖

Bu Makaleye Atıf Yap

GÜLER, İ., KILIÇ, H., ATALAY, M. A., RENDERS, D. P., ERÇAL, B. D. (2011). Metisilin dirençli Staphylococcus aureus suşlarının antibiyotiklere in-vitro duyarlılıkları. Dicle Tıp Dergisi, Cilt: 38 - Sayı: 4, 466–470. https://ajindex.com/articles/349856

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Margaret IP, Lyon DJ, Cheng AF. A longitudinal analysis of methicillin-resistant Staphylococcus aureus in a Hong Kong teaching hospital. Infect Contr Hosp Epidemiol 2004;25(2):126-9
  2. National Nosocomial Infections Surveillance (NNIS) System Report: Data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004; 32(8):470-85. 3.Wenzel RP, Reagen DR, Bertino JS, Baron EJ, Arias K. Methicillin-resistant Staphylococcus outbreak: a consensus panel’s defination and management guidelines. Am J Infect Control 1998;26(2):102-10
  3. Lowy FD. Staphylococcus aureus infections. New Engl J Med 1998;339(8):520-32
  4. Bilgehan H. Gram olumlu koklar: Klinik Mikrobiyoloji Özel Bakteriyoloji ve Bakteri Enfeksiyonları, 2 th edn. İzmir: Fakülteler Kitabevi Barış Yayınları, 2000: 239-68
  5. Boyce JM, Jackson MM, Pugliese G et al. Methicillin resistant Staphylococccus aureus (MRSA): a briefing for acute care hospitals and nursing facilities. Infect Control Hosp Epidemiol 1994;15(2):105-15
  6. Haznedaroğlu T. Metisilin dirençli S.aureus (MRSA) korunma ve kontrol. 2009:1-9. Ulaşılabileceği adres:
  7. Ünal S. MRSA problemi. ANKEM Derg 2009;23(Ek2):1-12
  8. Eliopoulos G: Antimicrobial agents for treatment of serious infections caused by resistant Staphylococcus aureus and enterococci. Eur J Clin Microbiol Infect Dis 2005;24(12):826-31
  9. Çetinkaya Y, Ünal S. Stafilokokal nazal taşıyıcılık önemi ve tedavisi. Hastane İnfeksiyon Derg 1999;3(1):22-32
  10. Diekema DJ, Pfaller MA, Schmitz FJ et al. Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the Sentry Antimicrobial Surveillance Program, 1997-1999. Clin Infect Dis 2001;32(Suppl 2):114-32
  11. National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing; 12th Informational Supplement M 100-S12, NCCLS, Villanova, PA (2002). 13.Tünger A. Staphylococcus aureus: Mikrobiyoloji, patogenez ve epidemiyoloji. In: Ulusoy S, Usluer G, Ünal S, eds. Gram-Pozitif Bakteri İnfeksiyonları, 1st edn. Ankara: Bilimsel Tıp Yayınevi, 2004:9-22
  12. Tambic A, Power EGM, Talsania H, Anthony RM, French GL. Analysis of outbreak of non-phage-typeable methicillin-resistant Staphylococcus aureus by using a randomyl amplified polymorphic DNA assay. J Clin Microbiol