Dergiler / Çocuk Enfeksiyon Dergisi / 2020 / Cilt: 14 - Sayı: 3

Fever, Malaise and Arthralgia: Brucellosis or Salmonellosis in the Differential Diagnosis in an Endemic Area

Ateş, Halsizlik ve Artralji: Endemik Bir Bölgede Ayırıcı Tanıda Bruselloz ve Salmonelloz

Sayfa
e106–e110
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

All patients are in remission except two cases of brucellosis with disease relapse in follow up, and one case with hemophagocytosis and prolonged disease and the need for additional chemotherapy.Conclusion: Despite effective eradication programmes for both diseases, they still remain important health problems and cause disease burden.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Brucellosis and salmonellosis are both infectious, zoonotic and endemic diseases in Turkey.
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Temel Bulgular & Veri:Material and Methods: We retrospectively analysed hospital records for gender, age, consumption of raw milk products, laboratory results, organ involvement, treatment choices and course of the disease.Results: Out of a total of 36 children, 30 were diagnosed with brucellosis and 6 with salmonellosis in two years.
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Sonuç & Katkı:All patients are in remission except two cases of brucellosis with disease relapse in follow up, and one case with hemophagocytosis and prolonged disease and the need for additional chemotherapy.Conclusion: Despite effective eradication programmes for both diseases, they still remain important health problems and cause disease burden.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Brucellosis and salmonellosis are both infectious, zoonotic and endemic diseases in Turkey. In this study, we aimed to report a group of pediatric patients admitted to the hospital with fever, malaise and arthralgia and diagnosed with either of the diseases. Material and Methods: We retrospectively analysed hospital records for gender, age, consumption of raw milk products, laboratory results, organ involvement, treatment choices and course of the disease.Results: Out of a total of 36 children, 30 were diagnosed with brucellosis and 6 with salmonellosis in two years. A total of 20 patients of 30 cases (66%) diagnosed with brucellosis notified exposure to animals. Except two of these patients, they usually confirmed that they consumed raw milk or cheese made with unpasteurized milk. Only 2 cases of the residual 6 cases diagnosed with salmonellosis had contact with animals and consumed raw milk or meat products. Their sources of infections remain unclear. Fever, malaise and arthralgia were most frequent symptoms, and hepatosplenomegaly was the most common extraarticular manifestation in both conditions. All patients are in remission except two cases of brucellosis with disease relapse in follow up, and one case with hemophagocytosis and prolonged disease and the need for additional chemotherapy.Conclusion: Despite effective eradication programmes for both diseases, they still remain important health problems and cause disease burden.

Abstract

Giriş: Bruselloz ve salmonelloz ülkemizde endemik olarak görülen enfeksiyöz ve zoonotik hastalıklardır. Bu çalışmada hastanemize ateş, halsizlik ve eklem ağrısı yakınması ile başvuran ve bu iki hastalık açısından tetkik edilerek biri ile tanı almış pediatrik olgular geriye dönük olarak incelenmesi amaçlanmıştır. Gereç ve Yöntemler: Hastaların yaş, cinsiyet, çiğ süt ve süt ürünü tüketim öyküleri, klinik ve laboratuvar bulguları, organ tutuluşları, tedavi uygulamaları ve prognozları retrospektif olarak değerlendirilerek sunulmuştur. Bulgular: İki yıllık süreçte toplam 36 olgunun 30’u bruselloz, 6’sı salmonelloz tanısı almıştır. Brusella tanısı alan 30 olgunun 20’si hayvan teması olduğunu ve 2 olgu dışında hepsi çiğ süt ve süt ürünü tüketimi olduğunu belirtmiştir. Salmonelloz tanısı alan 6 olgunun ise 2’sinin ailesi ise hayvancılıkla uğraşmakta olup, diğer olgularda enfeksiyon kaynağına dair bir gösterge bulunamamıştır. Ateş, halsizlik ve artralji en sık görülen semptomlar olup her iki hastalıkta hepatosplenomegali en sık görülen ekstraartiküler bulgudur. Bruselloz tanılı 17 olgudan 3’ünde relaps görülmüştür. İzlemde hemofagositoz gelişen ve kemoterapi ihtiyacı doğan bir olgu dışında tüm olgularda remisyon sağlanmıştır. Sonuç: Her iki hastalığa yönelik eradikasyon programlarının uygulanması ve kontrol çabalarına rağmen özellikle bruselloz, endemisite göstermesi açısından ülkemizde hâlâ önemli bir sağlık sorunu olarak karşımıza çıkmaktadır.

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Bu Makaleye Atıf Yap

ATIKAN, B. Y., AVCU, G. (2020). Fever, Malaise and Arthralgia: Brucellosis or Salmonellosis in the Differential Diagnosis in an Endemic Area. Çocuk Enfeksiyon Dergisi, Cilt: 14 - Sayı: 3, e106–e110. https://ajindex.com/articles/348562

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Kaynakça (13)

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