Dergiler / İzmir Tepecik Eğitim Hastanesi Dergisi / 2021 / Cilt: 31 - Sayı: 1

Is There any Other Disease Under the Newly Diagnosed Diabetes that is Difficult to Control?

Kontrol Edilmesi Zor Yeni Tanı Diyabette Altta Yatan Başka Bir Hastalık Olabilir Mi?

Sayfa
130–132
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We wanted to share a case with treatment-resistant hyperglycemia which is the cause of presentation of acromegaly.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:High levels of growth hormone and insulin-like growth factor 1 contribute to tissue proliferation and hypertrophy in patients with acromegaly mostly due to growth hormone-secreting pituitary adenoma.
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Temel Bulgular & Veri:Growth hormone also induces lipolytic activities and insulin resistance, so patients with acromegaly often present with impaired glucose tolerance and type 2 diabetes mellitus.
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Sonuç & Katkı:We wanted to share a case with treatment-resistant hyperglycemia which is the cause of presentation of acromegaly.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

High levels of growth hormone and insulin-like growth factor 1 contribute to tissue proliferation and hypertrophy in patients with acromegaly mostly due to growth hormone-secreting pituitary adenoma. Some phenotypic features of acromegaly that make us to consider in the differential diagnosis are excessive growth of the hands and feet and coarsening facial features. Growth hormone also induces lipolytic activities and insulin resistance, so patients with acromegaly often present with impaired glucose tolerance and type 2 diabetes mellitus. We wanted to share a case with treatment-resistant hyperglycemia which is the cause of presentation of acromegaly.

Abstract

Yüksek seviyedeki büyüme hormonu ve insülin benzeri büyüme faktörü 1, çoğunlukla büyüme hormonu salgılayan hipofiz adenomu nedeniyle akromegali hastalarında doku proliferasyonuna ve hipertrofiye katkıda bulunur. Ayırıcı tanıda düşünmemizi gerektiren akromegalinin bazı fenotipik özellikleri ellerin ve ayakların aşırı büyümesi ve yüzde kabalaşmadır. Büyüme hormonu ayrıca lipolitik etkilere ve insülin direncine neden olur, bu nedenle akromegali hastaları sıklıkla bozulmuş glukoz toleransı ve tip 2 diabetes mellitus ile ortaya çıkar. Akromegalinin ortaya çıkmasına neden olan tedaviye dirençli hiperglisemili bir vakayı paylaşmak istedik.

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Bu Makaleye Atıf Yap

KAYPAK, M. A., PATIR, D. Ç., ÖZALP, F. R., AKAR, H. (2021). Is There any Other Disease Under the Newly Diagnosed Diabetes that is Difficult to Control?. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 31 - Sayı: 1, 130–132. https://ajindex.com/articles/347809

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