Dergiler / JAREM / 2021 / Cilt: 11 - Sayı: 2

Successful Treatment of Chemotherapy-induced Symptoms with Granisetron as Alternative for Ondansetron Allergy

Ondansetron Alerjisinde Alternatif Granisetron ile Kemoterapiye Bağlı Semptomların Başarılı Şekilde Tedavisi

Dergi
JAREM
Sayfa
227–229
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Granisetron appears to be a safer potent alternative to ondansetron in patients with cancer receiving chemotherapy.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Ondansetron is a selective 5-hydroxy-tryptamine 3 receptor antagonist that is widely used as an antiemetic agent, especially for the preventive treatment of chemotherapy-induced nausea and vomiting.
📊
Temel Bulgular & Veri:Side effects of ondansetron are headache, dizziness, constipation, diarrhoea and hypersensitivity reactions such as anaphylaxis, which are very rarely described in the literature.
💡
Sonuç & Katkı:Granisetron appears to be a safer potent alternative to ondansetron in patients with cancer receiving chemotherapy.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Ondansetron is a selective 5-hydroxy-tryptamine 3 receptor antagonist that is widely used as an antiemetic agent, especially for the preventive treatment of chemotherapy-induced nausea and vomiting. Side effects of ondansetron are headache, dizziness, constipation, diarrhoea and hypersensitivity reactions such as anaphylaxis, which are very rarely described in the literature. Herein, we present a patient with Hodgkin lymphoma who developed urticaria secondary to ondansetron intake, had been receiving chemotherapy and has safely used granisetron as alternative. Granisetron appears to be a safer potent alternative to ondansetron in patients with cancer receiving chemotherapy.

Abstract

Ondansetron selektif 5-hidroksi-triptamin 3 reseptör antagonisti olan ve yaygın olarak, özellikle kemoterapiye bağlı bulantı ve kusmayı önlemede, kullanılan bir antiemetik ajandır. Ondansetronun yan etkileri baş ağrısı, baş dönmesi, kabızlık, diyare ve literatürde çok nadiren tanımlanan anafilaksi gibi hipersensitivite reaksiyonlarıdır. Bu raporda, kemoterapi alan ve ondansetrona bağlı ürtiker geliştiren ve güvenli şekilde alternatif granisetron kullanan Hodgkin lenfomalı bir olguyu sunmak istiyoruz. Granisetron kemoterapi alan onkoloji hastalarında güvenli ve güçlü bir ondansetron alternatifi olarak görünmektedir.

🔖

Bu Makaleye Atıf Yap

ÖZDEMİR, Ö., ERKUN, O. (2021). Successful Treatment of Chemotherapy-induced Symptoms with Granisetron as Alternative for Ondansetron Allergy. JAREM, Cilt: 11 - Sayı: 2, 227–229. https://ajindex.com/articles/347772

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (10)

  1. Chaudhary NK, John RR, Boddu D, Mahasampath G, Nesadeepam N, Mathew LG. Palonosetron is a better choice compared with ondansetron for the prevention of chemotherapy-induced nausea and vomiting (CINV) in a resource-limited pediatric oncology center: results from a randomized control trial. J Pediatr Hematol Oncol 2019; 41: 294-7
  2. Krammes SK, Jacobs T, Clark JM, Lutes RE. Effect of intravenous ondansetron on the QT interval of patients’ electrocardiograms. Pediatr Emerg Care 2018; 34: 38-41
  3. Kataja V, de Bruijn KM. Hypersensitivity reactions associated with 5- hydroxytryptamine (3)-receptor antagonists: a class effect? Lancet 1996; 2: 584-5
  4. Mehra KK, Gogtay NJ, Ainchwar R, Bichile LS. Hypersensitivity to intravenous ondansetron: a case report. J Med Case Rep 2008; 2: 274
  5. García Núñez I, Algaba Mármol MA, Reina Ariza E. Ondansetron hypersensitivity: a clinical diagnosis protocol and cross-reactivity study. J Investig Allergol Clin Immunol 2015; 25: 221-2
  6. Ross AK, Ferrero-Conover D. Anaphylactoid reaction due to the administration of ondansetron in a pediatric neurosurgical patient. Anesth Analg 1998; 87: 779-80
  7. Weiss KS. Anaphylactic reaction to ondansetron. Arch Intern Med 2001; 161: 2263
  8. Fernando SL, Broadfoot AJ. Ondansetron anaphylaxis: a case report and protocol for skin testing. J Med Case Rep2009; 102: 285-6
  9. Bousquet PJ, Co-Minh HB, Demoly P. Isolated urticaria to ondansetron and successful treatment with granisetron. Allergy 2005; 60: 543-4
  10. Demir AH. Anaphylactic reaction owing to ondansetron administration in a child with neuroblastoma and safe use of granisetron: a case report. J Pediatr Hematol Oncol 2010; 32: e341-2.