Dergiler / Journal of Clinical Research in Pediatric Endocrinology / 2021 / Cilt: 13 - Sayı: 2

Clinical Characteristics of 46,XX Males with Congenital Adrenal Hyperplasia

Sayfa
180–186
DOI
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In these cases,hysterectomy and bilateral salpingoopherectomy, genital corrective surgeries and testicular prosthesis operations were performed in avery wide age rage.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: To retrospectively evaluate the follow-up data in patients with 46,XX congenital adrenal hyperplasia (CAH) who were raisedmale.Methods: A national database was created.
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Temel Bulgular & Veri:The data of patients were asked to be recorded in the data form.Results: The median (range) age of diagnosis was three (0.1-18.3) years in 44 patients.
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Sonuç & Katkı:In these cases,hysterectomy and bilateral salpingoopherectomy, genital corrective surgeries and testicular prosthesis operations were performed in avery wide age rage.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: To retrospectively evaluate the follow-up data in patients with 46,XX congenital adrenal hyperplasia (CAH) who were raisedmale.Methods: A national database was created. The data of patients were asked to be recorded in the data form.Results: The median (range) age of diagnosis was three (0.1-18.3) years in 44 patients. Twenty nine cases were diagnosed after the ageof two years. Most (95.4%) cases were stage 4-5 virilized. Hysterectomy and bilateral salpingoopherectomy, at a median age of 7.25(2.4-25.3) years, was performed in 35 cases. Testicular prostheses were placed in 11 (25%) cases at a median age of 11.2 (2.8-17) years.The median final height was 149.2 (132.8-172) cms in 38 patients, including simple virilizing (n=18), salt-wasting (n=6), and 11-betahydroxylase (n=12). Of the 16 patients above the age of eighteen, university education was completed in 25%.Conclusion: It was seen that most (65.9%) of the 46,XX CAH cases raised male were diagnosed after two years of age. In these cases,hysterectomy and bilateral salpingoopherectomy, genital corrective surgeries and testicular prosthesis operations were performed in avery wide age rage.

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Bu Makaleye Atıf Yap

ERDEVE, Ş., AYCAN, Z., ÇETİNKAYA, S., ÖZTÜRK, A. P., BAŞ, F., POYRAZOĞLU, Ş., DARENDELİLER, F., OZSU, E., ŞIKLAR, Z., DEMİRAL, M., ÜNAL, E., ÖZBEK, M. N., GÜRBÜZ, F., YÜKSEL, B., EVLİYAOĞLU, O., AKYÜREK, N., BERBEROĞLU, M. (2021). Clinical Characteristics of 46,XX Males with Congenital Adrenal Hyperplasia. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 13 - Sayı: 2, 180–186. https://ajindex.com/articles/347737

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Kaynakça (14)

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