Dergiler / Viral Hepatitis Journal / 2020 / Cilt: 26 - Sayı: 3

Consideration Whether Hepatitis B Exists in Children Whose Mothers Suffer from Chronic Hepatitis B and These Mothers in Gestational Age

Kronik Hepatit B Enfeksiyonu Olan Annelerin Gebeliklerinde ve Çocuklarında Hepatit B Enfeksiyonun Değerlendirilmesi

Sayfa
124–130
DOI
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By informing both healthcare workers and society, awareness about examining pregnants for HBsAg during pregnancy should be increased.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Perinatal and intrauterine transmission of the hepatitis B virus (HBV) represents a major factor, leading to the development of chronic infection.
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Temel Bulgular & Veri:Results: Three hundred-one mothers and 616 children were included in the study.
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Sonuç & Katkı:By informing both healthcare workers and society, awareness about examining pregnants for HBsAg during pregnancy should be increased.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: Perinatal and intrauterine transmission of the hepatitis B virus (HBV) represents a major factor, leading to the development of chronic infection. This study aimed to explore the status of mothers and their children for hepatitis B (HB) infection during pregnancy and childhood, and whether active and passive immunoprophylaxis was administered to infants shortly after birth. Materials and Methods: We performed multicenter, retrospective research on voluntary hepatitis B surface antigen (HBsAg)-positive mothers admitted to infectious diseases polyclinics was performed. Mothers and their children were queried by a questionnaire about their HB infection status. Data from the electronic data recording system was scanned retrospectively. Results: Three hundred-one mothers and 616 children were included in the study. HBsAg was examined in 354 (57.4%) of pregnancies. Of 91 children with HBsAg positivity, 83 were not applied active and passive immunoprophylaxis after birth. Eight 276 babies received both immune prophylaxes after birth were then detected as HBsAg positive. On HBV examination, 148 children were found to encounter the HBV. HBsAg positivity rate was significantly higher in children born before 1997. Conclusion: The remarkable decrease in HBsAg positivity of children reveals the efficacy of national vaccination. By informing both healthcare workers and society, awareness about examining pregnants for HBsAg during pregnancy should be increased.

Abstract

Amaç: Hepatit B virüsünün (HBV) perinatal ve intrauterin bulaşı, kronik enfeksiyonun gelişmesine yol açan önemli bir faktörü temsil etmektedir. Bu çalışmada, annelerin ve çocuklarının hamilelik ve çocukluk döneminde hepatit B (HB) enfeksiyonu için değerlendirilme durumlarını ve doğumdan hemen sonra bebeklere aktif ve pasif immünoprofilaksi uygulanıp uygulanmadığının araştırılması amaçlandı. Gereç ve Yöntemler: Enfeksiyon hastalıkları polikliniğine başvuran gönüllü hepatit B yüzey antijeni (HBsAg)-pozitif annelere yönelik çok merkezli, retrospektif araştırma yaptık. Annelere ve çocuklarına HB enfeksiyonu durumları hakkında bir anket uygulandı. Elektronik veri kayıt sistemindeki verileri geriye dönük olarak tarandı. Bulgular: Üç yüz bir anne ve 616 çocuk çalışmaya dahil edildi. HBsAg gebeliklerin 354’ünde (%57,4) tetkik edildi. HBsAg pozitifliği olan 91 çocuğun 83’üne doğumdan sonra aktif ve pasif immünoprofilaksi uygulanmadığı saptandı. Doğumdan sonra her iki immün profilaksiyi de alan 276 bebekten 8’i HBsAg pozitif olarak tespit edildi. HBV incelemesinde, 148 çocuğun HBV ile karşılaştığı bulundu. HBsAg pozitiflik oranı 1997’den önce doğan çocuklarda anlamlı olarak daha yüksek olarak belirlendi. Sonuç: Çocukların HBsAg pozitifliğindeki dikkat çekici azalma, ulusal aşılamanın etkinliğini ortaya koymaktadır. Hem sağlık çalışanlarını hem de toplumu bilgilendirerek, hamilelik sırasında HBsAg için gebelerin tetkik edilmesi konusunda farkındalık artırılmalıdır

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Bu Makaleye Atıf Yap

YILDIZ, İ. E., TOSUN, S., ŞEN, S., ALTUNAL, L. N., UĞURLU, K., BAHŞİ, A. (2020). Consideration Whether Hepatitis B Exists in Children Whose Mothers Suffer from Chronic Hepatitis B and These Mothers in Gestational Age. Viral Hepatitis Journal, Cilt: 26 - Sayı: 3, 124–130. https://ajindex.com/articles/332623

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Kaynakça (10)

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