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Dergiler / Türk Toraks Dergisi / 2014 / Cilt: 15 - Sayı: 3

Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD

Gürol Şahin ULUTAŞ
AYLİN ÖZGEN ALPAYDIN
FATMA TANELİ
Cemile ÇETİNKAYA
Cevval ULMAN
YEŞİM GÜVENÇ DEMİRAĞCI
GÖNÜL DİNÇ HORASAN
Ayşın Şakar COŞKUN
Sayfa
106–111
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:as well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients.MATerIAL ANd MeTHods: Forty COPD patients and 40 healthy volunteers were included.
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Temel Bulgular & Veri:Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population.resULTs: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups.
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Sonuç & Katkı:However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

as well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients.MATerIAL ANd MeTHods: Forty COPD patients and 40 healthy volunteers were included. Participants were analysed in four groups according to their smoking status. Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population.resULTs: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups. CD4+/CD8+ T cell ratio and FEV1/FVC were found to have a mild positive correlation (r=0.295, p=0.022). A mild negative correlation was observed between smoking intensity and CD4+/CD8+ T cell ratio (r=-0.274, p=0.034).CoNCLUsIoN: We demonstrated a mild correlation between pulmonary functions and peripheral blood CD4+/CD8+ T cell ratio. However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction.

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Bu Makaleye Atıf Yap

ULUTAŞ, G. Ş., ALPAYDIN, A. Ö., TANELİ, F., ÇETİNKAYA, C., ULMAN, C., DEMİRAĞCI, Y. G., HORASAN, G. D., COŞKUN, A. Ş. (2014). Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD. Türk Toraks Dergisi, Cilt: 15 - Sayı: 3, 106–111. https://ajindex.com/articles/329609

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Kaynakça (4)

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