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Dergiler / Southern Clinics of Istanbul Eurasia / 2018 / Cilt: 29 - Sayı: 3

Predictors of Vesicoureteral Reflux in the Pretransplant Evaluation of Patients with End-Stage Renal Disease

Renal Transplantasyon Öncesi Değerlendirmede Vezikoüreteral Reflünün Belirteçleri

Ergün PARMAKSIZ
Meral MEŞE
Zuhal DOĞU
Zerrin BİCİK BAHÇEBAŞI
Sayfa
176–179
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The presence of VUR was not related to any cause of ESRD; therefore, VCUG is not needed in all cases as a part of pretransplant evaluation.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Voiding cystourethrography (VCUG) is widely performed in the pretransplant evaluation of patients with a history of urological disorders to detect vesicoureteral reflux (VUR).
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Temel Bulgular & Veri:Methods: A total of 319 pretransplant cases that underwent VCUG were retrospectively reviewed.
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Sonuç & Katkı:The presence of VUR was not related to any cause of ESRD; therefore, VCUG is not needed in all cases as a part of pretransplant evaluation.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Voiding cystourethrography (VCUG) is widely performed in the pretransplant evaluation of patients with a history of urological disorders to detect vesicoureteral reflux (VUR). The aim of this study was to evaluate the relationship between the primary etiology of end-stage renal disease (ESRD) and the prevalence of VUR, thereby determining the necessity for VCUG in pretransplant patients. Methods: A total of 319 pretransplant cases that underwent VCUG were retrospectively reviewed. Results: VCUG revealed VUR in 53 (16.6%) cases. VUR was left-sided in 21 (41.2%), rightsided in 18 (35.3%), and bilateral in 12 (3.8%), and grade 1 in 10 (19.6%), grade 2 in 19 (37.3%), grade 3 in 20 (39.2%), and grade 4 in 2 (3.9%). The etiology of ESRD was hypertension in 125 (39.2%), diabetes mellitus (DM) in 46 (14.4%), polycystic kidney disease (PKD) in 21 (6.6%), amyloidosis in 16 (5%), VUR in 11 (3.4%), and glomerulonephritis (GN) in 11 (3.4%). The incidence of VUR was significantly higher in female patients. Hypertension, DM, PKD, amyloidosis, and GN were not found to predict VUR. The rate of abnormal VCUG findings was similar in cases with secondary and idiopathic ESRD. Conclusion: The findings demonstrate that only sex was a predictor of VUR in pretransplant cases. The presence of VUR was not related to any cause of ESRD; therefore, VCUG is not needed in all cases as a part of pretransplant evaluation.

Abstract

Amaç: Voiding sistoüretrografi (VSUG) ürolojik hastalık öyküsü olan olguların transplantasyon öncesi vezikoüretral reflü (VUR) açısından değerlendirilmesinde sıklıkla kullanılır. Gereç ve Yöntem: Son dönem böbrek hastalığının (SDBH) etiyolojisi ile VUR prevalansı ilişkisini ve VSUG gerekliliğini değerlendirmeyi amaçladık. Transplantasyon öncesi VSUG uygulanan 319 hasta geriye dönük olarak değerlendirildi. Bulgular: Voiding sistoüretrografi ile 53 (%16.6) olguda VUR saptandı; 21 (%41.2) sol taraflı, 18 (%35.3) sağ taraflı, 12 (%3.8)iki taraflı; 10 (%19.6) grade 1, 19 (%37.3) grade 2, 20 (%39.2) grade 3 ve 2 (%3.9) grade 4 idi. SDBH sebebi 125 (%39.2) olguda hipertansiyon, 46 (%14.4) olguda, polya DM, 21 (%6.6) kistik böbrek hastalığı, 16 (%5) olguda amiloidoz, 11 (%3.4) olguda VUR ve 11 (%3.4) olguda glomerulonefrit idi. VUR sıklığı kadınlarda anlamlı olarak daha fazla bulundu. Hipertansiyon, DM, polikistik böbrek hastalığı, amiloidoz ve glomerulonefrit VUR belirteci olarak bulunmadı. Anormal VSUG bulgusu sıklığı sekonder ve idyopatik SDBH olgularında benzer bulundu. Sonuç: Çalışmamız, cinsiyetin VUR için anlamlı bir belirteç olduğu sonucunu ortaya koymuştur. VUR varlığı ile SDBH etiyolojisi arasında ilişki bulunmadı. Bu nedenle transplantasyon öncesi değerlendirmede VSUG yapılmasının gerekli olmadığı kanaatindeyiz. Anahtar Sözcükler: Böbrek nakli; vezikoüreteral reflü; voiding sistoüreterografi.

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Bu Makaleye Atıf Yap

PARMAKSIZ, E., MEŞE, M., DOĞU, Z., BAHÇEBAŞI, Z. B. (2018). Predictors of Vesicoureteral Reflux in the Pretransplant Evaluation of Patients with End-Stage Renal Disease. Southern Clinics of Istanbul Eurasia, Cilt: 29 - Sayı: 3, 176–179. https://ajindex.com/articles/314054

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