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Dergiler / Southern Clinics of Istanbul Eurasia / 2021 / Cilt: 32 - Sayı: 1

Myricetin Decreases Ovarian and Lung Tissue Injury Induced by Ovarian Torsion- Detorsion: A Biochemical Study

Yunus Emre TOPDAĞI
Ayhan TANYELİ
Fazile Nur EKİNCİ AKDEMİR
ERSEN ERASLAN
Mustafa CAN GÜLER
Sayfa
25–29
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: Myr demonstrated protection against lung and ovarian tissue injury in induced- TD experimental rats.

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Amaç & Hipotez:Objective: This study was designed to examine the effects of myricetin (Myr) on ovarian and lung tissue in rats with induced torsion-detorsion (TD) of bilateral ovaries to determine the potential to reduce oxidative damage.
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Temel Bulgular & Veri:Methods: The study group comprised 32 female Wistar albino rats randomly allocated to 4 groups: sham, ovarian TD, Myr/25 (25 mg/kg dose of Myr+TD), and Myr/50 (50 mg/kg dose of Myr+TD).
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Sonuç & Katkı:Conclusion: Myr demonstrated protection against lung and ovarian tissue injury in induced- TD experimental rats.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: This study was designed to examine the effects of myricetin (Myr) on ovarian and lung tissue in rats with induced torsion-detorsion (TD) of bilateral ovaries to determine the potential to reduce oxidative damage. Methods: The study group comprised 32 female Wistar albino rats randomly allocated to 4 groups: sham, ovarian TD, Myr/25 (25 mg/kg dose of Myr+TD), and Myr/50 (50 mg/kg dose of Myr+TD). Results: The total oxidant status (TOS), malondialdehyde (MDA) level, oxidative stress index (OSI), and myeloperoxidase (MPO) activity in both ovarian and lung tissues increased significantly in the ovarian TD group compared with the sham group, while the superoxide dismutase (SOD) and total antioxidant status (TAS) values decreased in the same group. In contrast, the SOD level increased, while MPO activity, the TOS, the OSI, and the MDA level decreased significantly in the Myr/25 and Myr/50 groups. Conclusion: Myr demonstrated protection against lung and ovarian tissue injury in induced- TD experimental rats.

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Bu Makaleye Atıf Yap

TOPDAĞI, Y. E., TANYELİ, A., AKDEMİR, F. N. E., ERASLAN, E., GÜLER, M. C. (2021). Myricetin Decreases Ovarian and Lung Tissue Injury Induced by Ovarian Torsion- Detorsion: A Biochemical Study. Southern Clinics of Istanbul Eurasia, Cilt: 32 - Sayı: 1, 25–29. https://ajindex.com/articles/313950

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