Dergiler / Respiratory Case Reports / 2018 / Cilt: 7 - Sayı: 1

Malignant Pleural Mesothelioma and Central Nervous System Metastases: Report of Two Cases

Malign Plevral Mezoltelyoma ve Santral Sinir Sistemi Metastazı: İki Olgu Sunumu

Sayfa
9–12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Presently described are the cases of 2 patients diagnosed with malignant mesothelioma and in whom a rarely seen cranial metastasis was determined.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:At the time of diagnosis of malignant pleural mesothelioma (MPM), distant metastases are rare, but can occur through the hematogenous route or an adjacent route.
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Temel Bulgular & Veri:Central nervous system (CNS) metastasis is rarely seen and the incidence is not known.
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Sonuç & Katkı:Presently described are the cases of 2 patients diagnosed with malignant mesothelioma and in whom a rarely seen cranial metastasis was determined.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

At the time of diagnosis of malignant pleural mesothelioma (MPM), distant metastases are rare, but can occur through the hematogenous route or an adjacent route. Central nervous system (CNS) metastasis is rarely seen and the incidence is not known. Metastases occur more often in patients with relatively prolonged survival following aggressive treatment. Metastasis most often occurs in the cerebral cortex, cerebellum, intracranial meninges, or the spinal cord. CNS metastases can be seen in all histological types of MPM. Presently described are the cases of 2 patients diagnosed with malignant mesothelioma and in whom a rarely seen cranial metastasis was determined.

Abstract

Malign plevral mezotelyoma (MPM)’de tanı esnasında uzak metastazlar nadiren görülür. Uzak metastaz hematojen yolla ya da komşuluk yoluyla olur. Santral sinir sistemi metastazı nadir görülür. Özellikle agresif tedaviler sonrasında nispeten surveyi uzayan hastalarda metastazlara daha sık rastlanır. Metastazlar sıklıkla serebral korteks, serebellum, intrakranial meninksler ve spinal kordda görülür. MPM' nin bütün histopatolojik tiplerinde görülebilir. Nadir görülmesi nedeniyle kranial metastaz saptanan malign mezotelyoma tanısı olan 2 olgumuzu sunmayı amaçladık.

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Bu Makaleye Atıf Yap

ÖZYÜREK, B. A., ERDOĞAN, Y., ÜNVER, M., ÖZDEMİR, T. Ş., DEMİRAĞ, F., KAYA, S. (2018). Malignant Pleural Mesothelioma and Central Nervous System Metastases: Report of Two Cases. Respiratory Case Reports, Cilt: 7 - Sayı: 1, 9–12. https://ajindex.com/articles/302436

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Kaynakça (7)

  1. Türkiye Mezotelyoma Çalışma Grubu Malign Plevral Mezotelyoma Türkiye Standartlar Rehberi 2014
  2. Tanrikulu AC, Abakay A, Kaplan MA, Küçüköner M, Palanci Y, Evliyaoglu O, et al. A clinical, radiographic and laboratory evaluation of prognostic factors in 363 patients with malignant pleural mesothelioma. Respiration 2010; 80:480-7. [CrossRef] 3. Vogelzang NJ. Malignant mesothelioma: diagnostic and management strategies for 1992. Semin Oncol 1992; 19:64-71
  3. Schouwink H, Korse CM, Bonfrer JM, Hart AA, Baas P. Prognostic value of the serum tumour markers Cyfra21-1 and tissue polypeptide antigen in malignant mesothelioma. Lung Cancer 1999; 25:25-32
  4. Şenyiğit A. Clinical assessment and variations in clinical presentation at malignant mesothelioma. Malignant Pleural Mesothelioma: A Changing Paradigm of Care. Istanbul, 27-28 May 2011
  5. Hartmann CA, Schütze H. Frequency of metastases and survival in histologic subtypes of pleural mesothelioma. Autopsy study of 106 cases. Pathologe 1992; 13:259-68
  6. Hulks G, Thomas JS, Waclawski E. Malignant pleural mesothelioma in western Glasgow 1980-6. Thorax 1989; 44:496-500. [CrossRef] 8. Huncharek M, Muscat J. Metastases in diffuse pleural mesothelioma: influence of histological type. Thorax 1987; 42:897-8. [CrossRef] 9. Whitwell F, Rawcliffe RM. Diffuse malignant pleural mesothelioma and asbestos exposure. Thorax 1971; 26:6-22. [CrossRef] 10. Adams VI, Unni KK, Muhm JR, Jett JR, Ilstrup DM, Bernatz PE. Diffuse malignant mesothelioma of pleura. Diagnosis and survival in 92 cases. Cancer 1986; 58:1540-51. [CrossRef] 11. Finn RS, Brims FJH, Gandhi A, Olsen N, Musk AW, Maskell NA, et al. Postmortem findings of malignant pleural mesothelioma: a two center study of 318 patients. Chest 2012; 142:1267-73. [CrossRef] 12. Schlienger M, Eschwege F, Blache R, Depierre. Malignant pleural mesothelioma. Study of 39 cases, 25 by autopsy. Bull Cancer 1969; 56:265-308
  7. Miller AC, Miettinen M, Schrump DS, Hassan R. Malignant mesothelioma and central nervous system metastases: Report of two cases, pooled analysis and systematic review. Ann Am Thorac Soc 2014; 11:1075-81. [CrossRef]