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Dergiler / Mikrobiyoloji Bülteni / 2011 / Cilt: 45 - Sayı: 4

Hastane kaynaklı metisiline dirençli stafilokok suşlarında vankomisin, teikoplanin, linezolid ve tigesiklin duyarlılığının E-test yöntemiyle değerlendirilmesi

Evaluation of vancomycin, teicoplanin, linezolide and tigecycline susceptibilities of nosocomial methicillin-resistant staphylococcus strains by E-test

Tamer Sami PELİTLİ
Salih CESUR
Sami KINIKLI
Hasan IRMAK
Ali Pekcan DEMİRÖZ
Esra KARAKOÇ
Sayfa
758–761
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Among glycopeptides, MIC50 and MIC90 values of vancomycin were found to be lower than that of teicoplanin.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The aim of this study was to determine the minimal inhibitory concentration (MIC) values of vancomycin, teicoplanin, tigecycline and linezolid in 100 methicillin-resistant staphylococci [21 methicillin-resistant Staphylococcus aureus (MRSA) and 79 methicillin-resistant coagulase negative staphylococcus (MR-CNS)] isolated as agents of nosocomial infection from patients at Ankara Training and Research Hospital between June 2005-March 2007.
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Temel Bulgular & Veri:For 21 MRSA strains $MIC _{50}, and MIC _{90}$ values were as follows: vancomycin 0.125 μg/ml and 1 μg/ml; teicoplanin 0.5 μg/ml and 3 μg/ml, linezolid 0.047 μg/ml and 0.19 μg/ml; tigecycline 0.094 μg/ml and 0.5 μg/ml, respectively.
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Sonuç & Katkı:Among glycopeptides, MIC50 and MIC90 values of vancomycin were found to be lower than that of teicoplanin.
🔬Tür:Araştırma Makalesi
📍Kapsam:2005 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

The aim of this study was to determine the minimal inhibitory concentration (MIC) values of vancomycin, teicoplanin, tigecycline and linezolid in 100 methicillin-resistant staphylococci [21 methicillin-resistant Staphylococcus aureus (MRSA) and 79 methicillin-resistant coagulase negative staphylococcus (MR-CNS)] isolated as agents of nosocomial infection from patients at Ankara Training and Research Hospital between June 2005-March 2007. The MIC values for vancomycin, teicoplanin, linezolid and tigecycline were tested by E-test method (AB Biodisk, Sweden). For 21 MRSA strains $MIC _{50}, and MIC _{90}$ values were as follows: vancomycin 0.125 μg/ml and 1 μg/ml; teicoplanin 0.5 μg/ml and 3 μg/ml, linezolid 0.047 μg/ml and 0.19 μg/ml; tigecycline 0.094 μg/ml and 0.5 μg/ml, respectively. For 79 MR-CNS strains $MIC _{50}, and MIC _{90}$ values were as follows: vancomycin 0.5 μg/ml and 2 μg/ml; teicoplanin 2 μg/ml and 4 μg/ml; linezolid 0.125 μg/ml and 0.25 μg/ml; tigecycline 0.38 μg/ml and 0.5 μg/ml, respectively. No resistance to vancomycin, teicoplanin, tigecycline and linezolid were determined in methicillin-resistant staphylococcus strains isolated from the inpatients in our hospital. Among glycopeptides, MIC50 and MIC90 values of vancomycin were found to be lower than that of teicoplanin.

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Bu Makaleye Atıf Yap

PELİTLİ, T. S., CESUR, S., KINIKLI, S., IRMAK, H., DEMİRÖZ, A. P., KARAKOÇ, E. (2011). Hastane kaynaklı metisiline dirençli stafilokok suşlarında vankomisin, teikoplanin, linezolid ve tigesiklin duyarlılığının E-test yöntemiyle değerlendirilmesi. Mikrobiyoloji Bülteni, Cilt: 45 - Sayı: 4, 758–761. https://ajindex.com/articles/299600

Kaynakça (12)

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