Dergiler / Mikrobiyoloji Bülteni / 2009 / Cilt: 43 - Sayı: 3

Bir askeri hastanede fetal menenjit etkeni olarak izole edilen Neisseria meningitidis serogrup W-135 suşlarının genotipik özellikleri

Genotypic characteristics of Neisseria meningitidis serogroup W-135 strains isolated as the agent of fatal meningitis in a military hospital

Sayfa
515–517
DOI
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These data demonstrated that along with ST-11 which is a known Hajj isolate, the ST-2754 strain causing meningococcal disease in Turkey beginning from the year 2003, should be carefully monitored.

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Amaç & Hipotez:The aim of this study was to describe the genetic characterization of a total of 6 Neisseria meningitidis serogroup W-135 strains isolated from patients with meningitis and carriers in a military hospital in 2007-2008.
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Temel Bulgular & Veri:Three distinct sequence types (STs) were identified: ST-11, ST-2754, ST-3751.
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Sonuç & Katkı:These data demonstrated that along with ST-11 which is a known Hajj isolate, the ST-2754 strain causing meningococcal disease in Turkey beginning from the year 2003, should be carefully monitored.
🔬Tür:Araştırma Makalesi
📍Kapsam:2007-2008 Verileri
⚙️Değişkenler:Neisseria meningitidis · serogrup W-135 · Askeri personel

Abstract

The aim of this study was to describe the genetic characterization of a total of 6 Neisseria meningitidis serogroup W-135 strains isolated from patients with meningitis and carriers in a military hospital in 2007-2008. Suspected colonies on modified Thayer-Martin medium plates were screened for oxidase reactivity and Gram stain. If gram-negative diplococci were present, a biochemical profile by the API NH system was used for species confirmation. Pulse field gel electrophoresis typing of Nhe/-digested DNA was performed by a previously described method. Multi-locus sequence typing (MLST) was performed using the standard primers as listed on the Neisseria MLST website. Three distinct sequence types (STs) were identified: ST-11, ST-2754, ST-3751. One of the clinical isolates was identified as the same sequence type with Hajj isolate (ST-11) and the isolate with ST-2754 was the same as the first Turkish clinical strain isolated in 2003. These data demonstrated that along with ST-11 which is a known Hajj isolate, the ST-2754 strain causing meningococcal disease in Turkey beginning from the year 2003, should be carefully monitored.

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Bu Makaleye Atıf Yap

KILIÇ, A., JOLLEY, K. A., BEŞİRBELLİOĞLU, B., KOÇAK, N., BEDİR, O., EYİGÜN, C. P., BAŞUSTAOĞLU, A. C. (2009). Bir askeri hastanede fetal menenjit etkeni olarak izole edilen Neisseria meningitidis serogrup W-135 suşlarının genotipik özellikleri. Mikrobiyoloji Bülteni, Cilt: 43 - Sayı: 3, 515–517. https://ajindex.com/articles/298892

Kaynakça (1)

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