Dergiler / Okmeydanı Tıp Dergisi / 2018 / Cilt: 34 - Sayı: 2

Does Tumor Localization of Operated NSCLC Have an Effect on Relapse and Survival?

Opere Küçük Hücre Dışı Akciğer Kanserinde Tümör Lokalizasyonunun Relaps ve Sağkalım Üzerine Etkisi Varmıdır?

Sayfa
71–75
DOI
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Conclusion: In patients with early stage NSCLC, there was no significant difference in relapse-free survival and overall survival in terms of tumor localization.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Our aim was to investigate the effect of tumor localization on relapse and survival in early stage lung cancer.
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Temel Bulgular & Veri:Material and Methods: In this multicentered, retrospective study, 182 early stage non small cell lung cancer patients were included between the years of 2012-2015.
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Sonuç & Katkı:Conclusion: In patients with early stage NSCLC, there was no significant difference in relapse-free survival and overall survival in terms of tumor localization.
🔬Tür:Araştırma Makalesi
📍Kapsam:2012-2015 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Our aim was to investigate the effect of tumor localization on relapse and survival in early stage lung cancer. Material and Methods: In this multicentered, retrospective study, 182 early stage non small cell lung cancer patients were included between the years of 2012-2015. The localizations of the primary tumor were determined as right upper lobe, right middle lobe, right lower lobe, left upper lobe, left middle lobe and left lower lobe. Overall survival and relapse-free survival rates were compared according to the lobes. Results: In total 182 patients were included. The median age was 61 years. Median follow up time was 24.8 months. Of the patients, 38 (20.9%) were stage 1, 82 (45.1%) were stage 2 and 62 (34.1%) were stage 3A. According to tumor localization, 23 (12.6%) were right lower lobe tumors, 13 (7.1%) were right middle lobe tumors, 61 (33.5%) were right upper lobe tumors, 27 (14.8%) were left lower lobe tumors, 58 (31.9%) were left upper lobe tumors. No significant effect was detected on relapse-free survival (p=0.862) and overall survival in terms of tumor localization. (p=0.750). Conclusion: In patients with early stage NSCLC, there was no significant difference in relapse-free survival and overall survival in terms of tumor localization.

Abstract

Amaç: Akciğer heterojen bir organdır bu yüzden erken evre akciğer kanserinde tümör lokalizasyonunun nükse ve sağkalıma etkisini araştırmak istedik. Gereç ve Yöntem: Çalışmaya retrospektif multisentrik olarak 2012-2015 tarihleri arasında 182 erken evre küçük hücre dışı akciğer kanserli hasta alındı. Primer tümörün sağ üst lob, sağ orta lob, sağ alt lob, sol üst lob ve sol alt loblardaki lokalizasyonları tespit edildi. Loblara göre relapssız sağkalım ve genel sağkalım oranları karşılaştırıldı. Bulgular: Toplam 182 hasta alındı. Median yaş 61 idi. Median takip süresi 24.8 ay idi. 38 (%20,9) evre 1, 82 (%45,1) evre 2, 62 (%34,1) evre 3A hasta vardı. Tümör lokalizasyonuna bakıldığında sağ alt lob 23 (%12,6), sağ orta lob 13 (%7,1), sağ üst lob 61 (%33,5), sol alt lob 27 (%14,8), sol üst lob 58 (%31,9) tümör vardı. Tümör lokalizasyonu relapssız sağ kalım (p=0,862) ve genel sağ kalım (p=0,750) açısından anlamlı bir farklılık göstermedi. Sonuç: Erken evre küçük hücre dışı akciğer kanserli hastalarda tümör lokalizasyonu relapssız sağkalım ve genel sağkalım açısından herhengi bir anlamlı farklılık göstermedi.

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Bu Makaleye Atıf Yap

GEREDELİ, C. (2018). Does Tumor Localization of Operated NSCLC Have an Effect on Relapse and Survival?. Okmeydanı Tıp Dergisi, Cilt: 34 - Sayı: 2, 71–75. https://ajindex.com/articles/291624

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