Dergiler / Marmara Medical Journal / 2018 / Cilt: 31 - Sayı: 2

Keton cisimlerinin insan meme kanseri hücrelerinde (MCF-7) canlılık üzerine etkileri

Effect of ketone bodies on viability of human breast cancer cells (MCF-7)

Sayfa
57–60
DOI
—
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Amaç: Kanser hücreleri aerobik koşullar altında Warburg etkisi

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Amaç: Kanser hücreleri aerobik koşullar altında Warburg etkisi
📊
Temel Bulgular & Veri:Amaç: Kanser hücreleri aerobik koşullar altında Warburg etkisi
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Sonuç & Katkı:Amaç: Kanser hücreleri aerobik koşullar altında Warburg etkisi
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Asetoasetat · Beta-hidroksibütirat · Keton cisimleri

Özet

Amaç: Kanser hücreleri aerobik koşullar altında Warburg etkisi

Abstract

Objective: Cancer cells exhibit an elevated glycolytic phenotype

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Bu Makaleye Atıf Yap

KAYA, Z., YILMAZ, A. M., YALÇIN, A. S. (2018). Keton cisimlerinin insan meme kanseri hücrelerinde (MCF-7) canlılık üzerine etkileri. Marmara Medical Journal, Cilt: 31 - Sayı: 2, 57–60. https://ajindex.com/articles/284291

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Kaynakça (2)

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  2. Poff AM, Ari C, Arnold P, Seyfried TN, D’Agostino DP. Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int J Cancer 2014; 135: 1711-20. doi: 10.1002/ijc.28809 Branco AF, Ferreira A, Simões RF, et al. Ketogenic diets: from cancer to mitochondrial diseases and beyond. Eur J Clin Invest 2016; 46: 285-98. doi: 10.1111/eci.12591 Aykin-Burns N, Ahmad IM, Zhu Y, Oberley LW, Spitz DR. Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochem J 2009; 418: 29-37. doi: 10.1042/BJ20081258 Wu GY, Thompson JR. The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick. Biochem J 1988; 255: 139-44. Schumacker P. Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 2006; 10: 175- 81. doi: 10.1016/j.ccr.2006.08.015 Veech RL, Chance B, Kashiwaya Y, et al. Ketone bodies, potential therapeutic uses. IUBMB Life 2001; 51: 241-7. doi: 10.1080/152165401753311780 Noh HS, Hah YS, Nilufar R, et al. Acetoacetate protects neuronal cells from oxidative glutamate toxicity. J Neurosci Res 2006; 83: 702-9. doi: 10.1002/jnr.20736. Cos S, Recio J, Sánchez-Barceló EJ. Modulation of the length of the cell cycle time of MCF-