Dergiler / Medeniyet Medical Journal / 2020 / Cilt: 35 - Sayı: 1

The Coexistence of Autoimmune Pancreatitis and Crohn’s Disease in an Adolescent Case

Adolesan Bir Olguda Otoimmun Pankreatit ve Crohn Hastalığı Birlikteliği

Sayfa
62–66
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

It should be kept in mind that inflammatory bowel disease may develop in the follow-up of autoimmune pancreatitis and autoimmune pancreatitis may be present in the etiology of chronic pancreatitis.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Although autoimmune pancreatitis is not seen in children frequently, it is included in the etiology of chronic pancreatitis.
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Temel Bulgular & Veri:A 16-year-old girl who was diagnosed with chronic pancreatitis 4 months previously, presented to the outpatient clinic with abdominal pain on the epigastric region, and left lower abdominal quadrant and bloody defecation.
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Sonuç & Katkı:It should be kept in mind that inflammatory bowel disease may develop in the follow-up of autoimmune pancreatitis and autoimmune pancreatitis may be present in the etiology of chronic pancreatitis.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Although autoimmune pancreatitis is not seen in children frequently, it is included in the etiology of chronic pancreatitis. A 16-year-old girl who was diagnosed with chronic pancreatitis 4 months previously, presented to the outpatient clinic with abdominal pain on the epigastric region, and left lower abdominal quadrant and bloody defecation. Remarkable laboratory test results were as follows: amylase: 109 U/L, lipase: 196 U/L, Ig G:13.70 g/L, IgG4:2.117 g/L, fecal calprotectin 573 µg/g. In the MRCP examination, revealed enlarged pancreas with a heterogeneous appearance, dilated main pancreatic duct. Colonoscopic and histopathological findings were consistent with inflammatory bowel disease. The case was diagnosed as Crohn’s disease coursing with autoimmune pancreatitis. Clinical and laboratory findings regressed after steroid treatment. Autoimmune pancreatitis is important in that it is rarely seen in children and though less frequently it is associated with Crohn’s disease. It should be kept in mind that inflammatory bowel disease may develop in the follow-up of autoimmune pancreatitis and autoimmune pancreatitis may be present in the etiology of chronic pancreatitis.

Abstract

Otoimmün pankreatit çocuklarda sık görülmese de, kronik pankreatit etiyolojileri içinde yer almaktadır. Dört ay önce kronik pankreatit tanısı alan 16 yaşındaki kız olgu, epigastrik bölge ve sol alt kadranda olan karın ağrısı ve kanlı dışkılama nedeniyle polikliniğe başvurdu. Laboratuvar tetkiklerinde amilaz: 109 U/L, lipaz: 196 U/L, Ig G:13.70 g/L, IgG4:2.117 g/L, fekal kalprotektin 573 µg/g saptandı. MRCP incelemesinde pankreas heterojen görünümde ve boyutu artmış, ana pankreatik kanal genişlemiş idi. Kolonoskopik inceleme ve histopatojik bulgular inflamatuvar bağırsak hastalığı ile uyumlu idi. Olguya otoimmun pankreatitle birlikte seyreden Crohn hastalığı tanısı konuldu. Steroid tedavisi sonrası klinik ve laboratuvar bulguları geriledi. Otoimmun pankreatit çocuklarda nadir görülmesi ve az sıklıkta da olsa Crohn hastalığı ile birliktelik göstermesi nedeniyle önemlidir. Otoimmun pankreatit takibinde inflamatuvar bağırsak hastalığı gelişebileceği ve kronik pankreatit etiyolojilerinde otoimmun pankreatit de olabileceği unutulmamalıdır.

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Bu Makaleye Atıf Yap

DOĞAN, G., AKGUN, O., OZDEMIR, S., UZUNER, E. G., POTUROGLU, S. (2020). The Coexistence of Autoimmune Pancreatitis and Crohn’s Disease in an Adolescent Case. Medeniyet Medical Journal, Cilt: 35 - Sayı: 1, 62–66. https://ajindex.com/articles/283211

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Kaynakça (10)

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