KaydedilenlerDerginizi ekleyin

Dergiler / Journal of Turkish Spinal Surgery / 2020 / Cilt: 31 - Sayı: 1

GIANT CELL TUMOR OF THE SACRUM AND CURRENT TREATMENT STRATEGIES

Ali ÖNER
Yunus Emre AKMAN
Sayfa
41–46
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In addition to intralesional curettage, high speed burr, electrocauterization, phenol and cement as adjuvant therapies can be used in the treatment of GCTs to decrease local recurrence in sacral cases while protecting neural tissues.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: Giant cell tumor (GCT) is a benign local aggressive tumor seen mostly in the third and fourth decades.
📊
Temel Bulgular & Veri:Materials and Methods: Between 2002 and 2018, online hospital database search was conducted for a diagnosis of sacrum and GCT.
💡
Sonuç & Katkı:In addition to intralesional curettage, high speed burr, electrocauterization, phenol and cement as adjuvant therapies can be used in the treatment of GCTs to decrease local recurrence in sacral cases while protecting neural tissues.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2002 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Giant cell tumor (GCT) is a benign local aggressive tumor seen mostly in the third and fourth decades. Sacrum is the most commonly affected spinal region, followed by thoracic, cervical and lumbar regions. Aim of this study is to evaluate the results of surgical treatment in sacral GCT and review the treatment options of GCT in this uncommon location. Materials and Methods: Between 2002 and 2018, online hospital database search was conducted for a diagnosis of sacrum and GCT. Patient records were evaluated for recurrence and called for last follow-up. Results: There were four patients (one male, three female) operated due to sacral GCT, included in the study. Mean follow-up was 49 (25 to 82) months. High speed burr, electrocauterization and phenol were used as adjuvant treatment in all cases. Cementing was used in two patients. Conclusion: En bloc resection is the most effective treatment method with the lowest recurrence rate, yet it has the highest morbidity. In addition to intralesional curettage, high speed burr, electrocauterization, phenol and cement as adjuvant therapies can be used in the treatment of GCTs to decrease local recurrence in sacral cases while protecting neural tissues.

🔖

Bu Makaleye Atıf Yap

ÖNER, A., AKMAN, Y. E. (2020). GIANT CELL TUMOR OF THE SACRUM AND CURRENT TREATMENT STRATEGIES. Journal of Turkish Spinal Surgery, Cilt: 31 - Sayı: 1, 41–46. https://ajindex.com/articles/270687

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Orguc S, Arkun R. Primary Tumors of the Spine. Semin Musculoskelet Radiol. 2014;18:280-99
  2. Dang L, Liu X, Dang G, Jiang L, Wei F, Yu M, et al. Primary tumors of the spine: a review of clinical features in 438 patients. J Neurooncol. 2015;121:513-20
  3. Murphey MD, Nomikos GC, Flemming DJ, Gannon FH, Temple HT, Kransdorf MJ. From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. RadioGraphics. 2001;21:1283-309
  4. Parman LM, Murphey MD. Alphabet Soup: Cystic Lesions of Bone. Semin Musculoskelet Radiol. 2000;4:0089-0102
  5. Skubitz KM, Cheng EY, Clohisy DR, Thompson RC, Skubitz APN. Gene expression in giant cell tumors. J Lab Clin Med. 2004;144:193-200
  6. Morgan T, Atkins GJ, Trivett MK, Johnson SA, Kansara M, Schlicht SL, et al. Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB. Am J Pathol. 2005;167:117-28
  7. Martin C, McCarthy EF. Giant cell tumor of the sacrum and spine: series of 23 cases and a review of the literature. Iowa Orthop J. 2010;30:69-75
  8. Gong LH, Liu WF, Ding Y, Zhang W, Yang YK, Yu F, et al. Clinical, radiologic and pathologic features of giant cell tumor of bone treated with denosumab. Zhonghua Bing Li Xue Za Zhi. 2018;8;47:449-54
  9. Kim SC, Cho W, Chang U-K, Youn SM. Clinical Outcome of Treatment for Patients with Giant Cell Tumor in Spine. J Korean Neurosurg Soc. 2015;58:248-53
  10. Domovitov SV, Chandhanayingyong C, Boland PJ, McKeown DG, Healey JH. Conservative surgery in the treatment of giant cell tumor of the sacrum: 35 years’ experience. J Neurosurg Spine. 2016;24:228-40
  11. Jamshidi K, Bagherifard A, Mirzaei A, Bahrabadi M. Giant Cell Tumor of the sacrum: Series of 19 patients and Review of the Literature. Arch Bone Jt Surg. 2017;5:443-50
  12. Hussain S, Makhdoomi R, Khursheed N, Aiman A, Bhat N. Giant Cell Tumor of Sacrum: a Report of Two Cases (Internet). J Turk Spinal Surg. 2015;26:47-50
  13. Dürr HR, Maier M, Jansson V, Baur A, Refior HJ. Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone. Eur J Surg Oncol. 1999;25:610-8
  14. Campanacci M, Baldini N, Boriani S, Sudanese A. Giant-cell tumor of bone. J Bone Joint Surg Am. 1987;69:106-14
  15. Boriani S, Bandiera S, Casadei R, Boriani L, Donthineni R, Gasbarrini A, et al. Giant cell tumor of the mobile spine: a review of 49 cases. Spine (Phila Pa 1976). 2012;37:E