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Dergiler / Journal of Clinical Research in Pediatric Endocrinology / 2015 / Cilt: 7 - Sayı: 2

Vitamin D Deficiency and Hashimoto's Thyroiditis in Children and Adolescents: a Critical Vitamin D Level for This Association?

SAADET OLCAY EVLİYAOĞLU
Manolya ACAR
Bahar ÖZCABI
ETHEM ERGİNÖZ
Feride BUCAK
OYA ERCAN
MİNE KUCUR
Sayfa
128–133
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The mechanism for this association is not clear.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Vitamin D has been suggested to be active as an immunomodulator in autoimmune diseases such as Hashimoto's thyroiditis (HT).
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Temel Bulgular & Veri:The goal of the present study was to investigate the vitamin D status in HT patients.Methods: This prevalence case-control study was conducted on 90 patients with HT (of ages 12.32±2.87 years) and 79 age-matched healthy controls (11.85±2.28 years).
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Sonuç & Katkı:The mechanism for this association is not clear.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Vitamin D has been suggested to be active as an immunomodulator in autoimmune diseases such as Hashimoto's thyroiditis (HT). The goal of the present study was to investigate the vitamin D status in HT patients.Methods: This prevalence case-control study was conducted on 90 patients with HT (of ages 12.32±2.87 years) and 79 age-matched healthy controls (11.85±2.28 years). Serum 25-hydroxyvitamin D3 [25(OH)D3] levels were measured in all 169 subjects.Results: The prevalence of vitamin D deficiency in HT patients (64 of 90; 71.1%) was significantly higher than that in the control group (41 of 79; 51.9%) (p=0.025). Mean serum 25(OH)D3 level in the HT group was significantly lower compared to the control group (16.67±11.65 vs. 20.99±9.86 ng/mL, p=0.001). HT was observed 2.28 times more frequently in individuals with 25(OH)D3 levels <20 ng/mL (OR: 2.28, CI: 1.21-4.3).Conclusion: Vitamin D deficiency is associated with HT in children and adolescents. Levels lower than 20 ng/mL seem to be critical. The mechanism for this association is not clear.

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Bu Makaleye Atıf Yap

EVLİYAOĞLU, S. O., ACAR, M., ÖZCABI, B., ERGİNÖZ, E., BUCAK, F., ERCAN, O., KUCUR, M. (2015). Vitamin D Deficiency and Hashimoto's Thyroiditis in Children and Adolescents: a Critical Vitamin D Level for This Association?. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 7 - Sayı: 2, 128–133. https://ajindex.com/articles/270526

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Kaynakça (7)

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