Dergiler / İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi / 2020 / Cilt: 10 - Sayı: 2

Evaluation of the Effects of “High-Flow Nasal Cannula Oxygenation” Therapy on Vital Signs in Infants Diagnosed as Severe Acute Bronchiolitis Who Are Unresponsive to Conventional Therapy

Konvansiyonel Tedaviye Cevapsız Ağır Akut Bronşiyolitli İnfantlarda “Yüksek Akımlı Nazal Oksijen” Tedavisinin Vital Bulgular Üzerine Etkisi

Sayfa
190–196
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Our data about efficacy of HFNC therapy should be evaluated with multicenter studies.

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Amaç & Hipotez:Objective: High-flow nasal cannula oxygenation (HFNC) therapy is reported to provide a significant imp-rovement in vital findings in pediatric patients who develop respiratory distress during follow- up of acute bronchiolitis.
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Temel Bulgular & Veri:Method: This observational, single center study included patients (1-24 months) diagnosed with severe acute bronchiolitis who were administered HFNC therapy (1-2 L/kg/min with F&P Airvo 2TM optiflow device) between October 2017 and March 2018.
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Sonuç & Katkı:Our data about efficacy of HFNC therapy should be evaluated with multicenter studies.
🔬Tür:Araştırma Makalesi
📍Kapsam:2017 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: High-flow nasal cannula oxygenation (HFNC) therapy is reported to provide a significant imp-rovement in vital findings in pediatric patients who develop respiratory distress during follow- up of acute bronchiolitis. In our study, we aimed to evaluate the effects of HFNC therapy on vital findings in infants diagnosed with severe acute bronchiolitis and also, we compared the mean duration and the number of hospitalizations of these patients in the intensive care unit with the period where HFNC was not available in our center. Method: This observational, single center study included patients (1-24 months) diagnosed with severe acute bronchiolitis who were administered HFNC therapy (1-2 L/kg/min with F&P Airvo 2TM optiflow device) between October 2017 and March 2018. Duration of hospitalization, respiratory and heart rate, blood pressure, and saturation of oxygen change values at 1st, 6th, 12th, and 24th hours of HFNC therapy were evaluated. Results: A total of 41 patients was included in the study, 66% (n=27) were boys, the mean age was 7.5±5.6 months, and the mean body weight was 7.5±2.2 kilograms. Of all patients, 32 (78%) were followed up in the ward, and 9 (22%) were transferred to pediatric intensive care unit. Heart and respiratory rates were significantly decreased and saturation of oxygen was significantly increased at 1st, 6th, 12th, and 24th hours. No significant difference was found in the duration of hospitalization compared to the period where HFNC was not available. Conclusion: In our study, HFNC therapy significantly decreased respiratory and heart rate, and significantly improved SpO2. Our data about efficacy of HFNC therapy should be evaluated with multicenter studies.

Abstract

Amaç: Yüksek akımlı nasal oksijen (YANKO) tedavisinin, akut bronşiolit izleminde respiratuar distres geliş-tiren çocuk hastalarda vital bulguları belirgin düzelttiği belirtilmektedir. Çalışmamızda ağır akut bronşiolit tanılı infantlarda YANKO tedavisinin vital bulgulara etkisini değerlendirmeyi amaçladık ve ayrıca bu hasta-ların merkezimizde YANKO bulunmadığı sürede yoğun bakım ünitesinde yatış süresi ve sayılarını karşılaş-tırdık. Yöntem: Bu gözlemsel, tek merkezli çalışmaya, Ekim 2017 ile Mart 2018 arasında YANKO tedavisi (F&P Airvo 2TM optiflow cihazı ile 1-2 L/kg/dk.) uygulanan ağır akut bronşiolit tanılı hastalar (1-24 ay) dahil edildi. Hastane yatış süresi, YANKO tedavisinin 1., 6., 12. ve 24. saaatlerindeki solunum ve kalp hızı, kan basıncı ve oksijen saturasyonu değişimleri değerlendirildi. Bulgular: Çalışmaya toplam 41 hasta dahil edildi, % 66’sı (n=27) erkekti, ortalama yaş 7,5±5,6 ay ve orta-lama vücut ağırlığı 7,5±2,2 kilogramdı. Tüm hastaların 32’si (%78) serviste takip edildi ve 9’u (%22) pedi-atrik yoğun bakım ünitesine devir edildi. Birinci, 6., 12. ve 24. saatlerde, kalp ve solunum hızı anlamlı azaldı, oksijen saturasyon değeri anlamlı arttı. Hastanede yatış süresinde, YANKO’nun olmadığı döneme göre anlamlı bir fark bulunmadı. Sonuç: Çalışmamızda YANKO tedavisi kalp ve solunum hızını anlamlı azaltırken ve oksijen saturasyonunu anlamlı olarak arttırdı. YANKO tedavisinin etkinliği ile ilgili verilerimiz çok merkezli çalışmalarla değerlendirilmelidir.

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Bu Makaleye Atıf Yap

KOÇOĞLU, M., GÜNGÖR, A., BURHAN, B. Y., KARAGÖL, C., ÖDEN, A. A. (2020). Evaluation of the Effects of “High-Flow Nasal Cannula Oxygenation” Therapy on Vital Signs in Infants Diagnosed as Severe Acute Bronchiolitis Who Are Unresponsive to Conventional Therapy. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, Cilt: 10 - Sayı: 2, 190–196. https://ajindex.com/articles/268673

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