Dergiler / İzmir Tepecik Eğitim Hastanesi Dergisi / 2020 / Cilt: 30 - Sayı: 1

Troponin-T Levels Can Predict Left Ventricle Remodeling in Chronic Hemodialysis Patients

Troponin-T Düzeyleri Kronik Hemodiyaliz Hastalarında Sol Ventrikül Remodelingini Öngörebilir

Sayfa
12–18
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, cTnT could be used as a marker of LV geometric pattern and as a method for planning the treatment modalities in hemodialysis patients.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: Cardiac troponin T (cTnT) is an important marker in patients with chronic renal failure (CRF) in the prediction of cardiovascular outcomes.
📊
Temel Bulgular & Veri:Method: Sixty-one patients who underwent hemodialysis three times a week for more than 3 months (mean 19 months) were included the study.
💡
Sonuç & Katkı:In conclusion, cTnT could be used as a marker of LV geometric pattern and as a method for planning the treatment modalities in hemodialysis patients.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Cardiac troponin T (cTnT) is an important marker in patients with chronic renal failure (CRF) in the prediction of cardiovascular outcomes. We aimed to evaluate whether cTnT levels will provide further information about left ventricular geometric pattern in CRF as the result of patient’s volume status and efficacy of hemodialysis. Method: Sixty-one patients who underwent hemodialysis three times a week for more than 3 months (mean 19 months) were included the study. One day before the mid-dialysis session, blood samples were taken from the patients in the hemodialysis program and cTnT was studied. All patients underwent echocardiographic examination one day before the second hemodialysis session of the week by the same cardiologist. Results: When the groups were compared in terms of echocardiographic volume parameters; left atrium diameter, left ventricle (LV) mass, LV mass index were found to be higher in the cTnT positive group. The eccentric LV hypertrophy pattern was significantly more frequent in the cTnT-positive group (p:0.04). Conclusion: cTnT levels increase in hemodialysis patients with eccentric LV hypertrophy as the result of hypervolemia. In conclusion, cTnT could be used as a marker of LV geometric pattern and as a method for planning the treatment modalities in hemodialysis patients.

Abstract

Amaç: Kronik böbrek yetmezliği (KBY) olan hastalarda kardiyak troponin T (cTnT), kardiyovasküler sonuçları öngörmede önemli bir belirteçtir. cTnT düzeylerinin, hemodiyalizin etkinliği ve hastanın volüm durumunun bir sonucu olarak; KBY’ deki sol ventrikül geometrik paterni hakkında daha fazla bilgi sağlayıp sağlamadığını değerlendirmeyi amaçladık. Yöntem: Çalışmaya 3 aydan fazla (haftada 19 ay), haftada üç kez hemodiyaliz yapılan, altmış bir hasta dahil edildi. Hemodiyaliz programındaki hastalardan orta diyaliz seansından bir gün önce kan örnekleri alındı ve cTnT çalışıldı. Tüm hastalara aynı kardiyolog tarafından haftanın ikinci hemodiyaliz seansından bir gün önce ekokardiyografik inceleme yapıldı. Bulgular: Gruplar ekokardiyografik volüm parametreleri açısından karşılaştırıldığında; cTnT pozitif grupta sol atriyum çapı, sol ventrikül (SV) kitlesi, SV kitle indeksi daha yüksek bulundu. Egzantrik SV hipertrofi paterni, cTnT-pozitif grupta anlamlı olarak daha sıktı (p:0,04). Sonuç: Hipervolemiye sekonder gelişen egzantrik sol ventrikül hipertrofisi olan hemodiyaliz hastalarında cTnT artmaktadır. Sonuç olarak, cTnT hemodiyaliz hastalarında LV geometrik paterninin bir yol göstericisi ve tedavi yöntemlerinin planlanması için bir yöntem olarak kullanılabilir.

🔖

Bu Makaleye Atıf Yap

EKMEKCİ, C., ÇOLAK, H., BAYTURAN, Ö., KÜRŞAT, S., TEZCAN, U. K., BİLGE, A. R. (2020). Troponin-T Levels Can Predict Left Ventricle Remodeling in Chronic Hemodialysis Patients. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 30 - Sayı: 1, 12–18. https://ajindex.com/articles/268341

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Mallamaci F, Zoccali C, Parlongo S, et al. Troponin is related to left ventricular mass and predicts all-cause and cardiovascular mortality in hemodialysis patients. Am J Kidney Dis. 2002
  2. [CrossRef] 2. Dierkes J, Domrose U, Westphal S, et al. Cardiac troponin T predicts mortality in patients with end-stage renal disease. Circulation. 2000
  3. [CrossRef] 3. Parfrey PS, Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors for left ventricular disorders in chronic uraemia. Nephrol Dial Transplant. 1996
  4. [CrossRef] 4. Park M, Hsu CY, Li Y, et al. Associations between kidney function and subclinical cardiac abnormalities in CKD. J Am Soc Nephrol. 2012
  5. [CrossRef] 5. American Society of Echocardiography Recommendations for Use of Echocardiography in Clinical Trials J Am Soc Echocardiogr. 2004
  6. [CrossRef] 6. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978
  7. [CrossRef] 7. Importance of imaging method over imaging modality in noninvasive determination of left ventricular volumes and ejection fraction: assessment by two- and three-dimensional echocardiography and magnetic resonance imaging. J Am Coll Cardiol. 2000 Feb
  8. 35(2):477-84. [CrossRef] 8. Devereux RB, Alonso DR, Lutas EM, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986
  9. [CrossRef] 9. Casale PN, Devereux RB, Milner M, et al. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986
  10. [CrossRef] 10. Devereux RB, de Simone G, Koren MJ, Roman MJ, Laragh JH: Left ventricular mass as a predictor of development of hypertension. Am J Hypertens. 1991
  11. [CrossRef] 11. Levy D, Savage DD, Garrison RJ, Anderson KM, Kannel WB, Castelli WP. Echocardiographic criteria for left ventricular hypertrophy: the Framingham Heart Study. Am J Cardiol. 1987
  12. [CrossRef] 12. Ganau A, Devereux RB, Roman MJ, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol. 1992
  13. [CrossRef] 13. Foley RN, Parfrey PS, Sarnak MJ. Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol. 1998
  14. 9[Suppl]:16-23. 14. Myhre PL, Omland T, Sarvari