Dergiler / European Oral Research / 2019 / Cilt: 53 - Sayı: 3

The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis

Sayfa
125–131
Yayın Tarihi
2019-10-01
DOI
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Conclusion: ESWT in these parameters was not positively effective in bone maturation during consolidation when applied before osteotomy or both before and after osteotomy.

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Amaç & Hipotez:Purpose: This study aims to evaluate the effects of extracorporeal shock wave therapy applied before and/or immediately after the osteotomy on the maturation during the consolidation phase.
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Temel Bulgular & Veri:Materials and Methods: 21 female New Zealand rabbits were used in the study.
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Sonuç & Katkı:Conclusion: ESWT in these parameters was not positively effective in bone maturation during consolidation when applied before osteotomy or both before and after osteotomy.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:bone regeneration · distraction osteogenesis · dual-energy x-ray absorptiometry

Abstract

Purpose: This study aims to evaluate the effects of extracorporeal shock wave therapy applied before and/or immediately after the osteotomy on the maturation during the consolidation phase. Materials and Methods: 21 female New Zealand rabbits were used in the study. Subjects were divided randomly into three groups: Control (Distraction without ESWT), A (Distraction +ESWT After Osteotomy), AB (Distraction+ESWT After and Before Osteotomy). ESWT (500 pulses, 5 Hz, 0.19 mJ/mm2 energy flux density) was applied to group A and group AB after 5, 12 and 19 days after osteotomy and group AB only on days 7,14 and 21 before osteotomy. On the 28th day of the consolidation period, all subjects were sacrificed. Dual-energy x-ray absorptiometry (DEXA) was used to determine bone mineral density (BMD) and bone mineral content (BMC), and stereological methods were used to determine the new bone, connective tissue and neovascularization volumes. Results: As a result of DEXA examinations made on the 1st and 4th week of consolidation, there was no significant difference between groups regarding BMD and BMC values. According to the results of stereological examination, when the connective tissue and new bone tissue were evaluated, higher values were observed in AB when compared to A, and in AB and A compared to the control group, but the differences are not statistically significant. There was no difference between the groups in terms of neovascularization. Conclusion: ESWT in these parameters was not positively effective in bone maturation during consolidation when applied before osteotomy or both before and after osteotomy.

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Bu Makaleye Atıf Yap

SENEL, E., OZKAN, E., BEREKET, M. C., ONGER, M. E. (2019). The assessment of new bone formation induced by unfocused extracorporeal shock wave therapy applied on pre-surgical phase of distraction osteogenesis. European Oral Research, Cilt: 53 - Sayı: 3, 125–131. https://ajindex.com/articles/242912

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Kaynakça (11)

  1. Raza H, Saltaji H, Kaur H, Flores-Mir C, El-Bialy T. Effect of Low-Intensity Pulsed Ultrasound on Distraction Osteogenesis Treatment Time: A Meta-analysis of Randomized Clinical Trials. J Ultrasound Med 2016;35(2):349-358
  2. Zimmermann C, Thurmuller M, Troulis D, Perrott B, Rahn L, Kaban B. Histology of the porcine mandibular distraction wound. Int J Oral Maxillofac Surg 2005;34(4), 411-419
  3. Jiang X, Zhang Y, Fan X, Deng X, Zhu Y, Li F. The effects of hypoxia-inducible factor (HIF)-1α protein on bone regeneration during distraction osteogenesis: an animal study. Int J Oral Maxillofac Surg 2016;45(2):267-272
  4. Freddo AL, Giongo CC, Ponzoni D, Corsetti A, Puricelli E. Influence of a Magnetic Field and Laser Therapy on the Quality of Mandibular Bone During Distraction Osteogenesis in Rabbits. J Oral Maxillofac Surg 2016;74(11):2287.e1-2287.e8
  5. Williams PR, Smith NC, Cooke-Yarborough C, Little DG. Bisphosphonates and nephrocalcinosis in a rabbit leg lengthening model: a histological and therapeutic comparison. Pharmacol Toxicol 2001;89:149-152
  6. Primrose AC, Broadfoot E, Diner PA, Molina F, Moos KF, Ayoub AF. Patients' responses to distraction osteogenesis: a multi-centre study. Int J Oral Maxillofac Surg 2005;34(3):238-242
  7. Zhu S, Song D, Jiang X, Zhou H, Hu J. Combined effects of recombinant human BMP-2 and Nell-1 on bone regeneration in rapid distraction osteogenesis of rabbit tibia. Injury 2011;42(12):1467-1473
  8. Yonezawa H, Harada K, Ikebe T, Shinohara M, Enomoto S. Effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone consolidation on distraction osteogenesis: a preliminary study in rabbit mandibles. J Craniomaxillofac Surg 2006;34(5):270-276
  9. Castro-Govea Y, Cervantes-Kardasch VH, Borrego-Soto G, Martínez-Rodríguez HG, Espinoza-Juarez M, Romero-Díaz V, Marino-Martínez IA, Robles-Zamora A, Álvarez-Lozano E, Padilla-Rivas GR, Ortiz-López R, Lara-Arias J, Vázquez-Juárez J, Rojas-Martínez A. Human bone morphogenetic protein 2-transduced mesenchymal stem cells improve bone regeneration in a model of mandible distraction surgery. J Craniofac Surg 2012;23(2):392-396
  10. Alp YE, Taskaldiran A, Onder ME, Karahan S, Kocyigit ID, Atil F, Tekin U. Effects of Local Low-Dose Alendronate Injections Into the Distraction Gap on New Bone Formation and Distraction Rate on Distraction Osteogenesis. J Craniofac Surg 2017;28(8):2174-2178
  11. Taylor BA, Bezuhly M, Brace M, Carter M, Hong P. Effect of strontium citrate on bone conso