Dergiler / GORM:Gynecology Obstetrics & Reproductive Medicine / 2005 / Cilt: 11 - Sayı: 1

Two different regimens of intravaginal plus oral and intravaginal misoprostol for termination of second trimester pathologic pregnancies

Sayfa
31–33
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

CONCLUSION: Both intravaginal plus oral and intravaginal administrations of misoprostol can be accepted as efficient and safe, but pregnants with previous cesarean sections should intensively be followed.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:OBJECTİVE: To compare the safety and efficacy of two different regimens of misoprostol for termination of second trimester pathologic pregnancies.
📊
Temel Bulgular & Veri:MATERİALS AND METHODS: 150 women with 14-28 weeks gestations and with indications of termination of their pregnancies were enrolled. 89 women (Group A) were administered two intravaginal tablets and continued to oral half tablet in every two hours unless active contractions began. 61 pregnants (Group B) were administered one intravaginally tablet and continued to one intravaginal tablet in every three hours.
💡
Sonuç & Katkı:CONCLUSION: Both intravaginal plus oral and intravaginal administrations of misoprostol can be accepted as efficient and safe, but pregnants with previous cesarean sections should intensively be followed.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Gebelik trimester · ikinci · Gebelik

Abstract

OBJECTİVE: To compare the safety and efficacy of two different regimens of misoprostol for termination of second trimester pathologic pregnancies. MATERİALS AND METHODS: 150 women with 14-28 weeks gestations and with indications of termination of their pregnancies were enrolled. 89 women (Group A) were administered two intravaginal tablets and continued to oral half tablet in every two hours unless active contractions began. 61 pregnants (Group B) were administered one intravaginally tablet and continued to one intravaginal tablet in every three hours. Procedures were repeated up to five times. RESULTS: There were no significant differences in clinical properties of the groups. In Group A patients total dose was significantly higher than Group B (1251.6 versus 806.4 mcg). There were no significant difference in induction labor intervals (13.6 versus 11.9 hours) and failure rates (16.8% versus 13.1%) side effects were similar except on uterine rupture in Group A in a case with a previous cesarean section. CONCLUSION: Both intravaginal plus oral and intravaginal administrations of misoprostol can be accepted as efficient and safe, but pregnants with previous cesarean sections should intensively be followed.

🔖

Bu Makaleye Atıf Yap

TANER, C. E., NAYKI, Ü. A., EGE, A., MIZRAK, T. (2005). Two different regimens of intravaginal plus oral and intravaginal misoprostol for termination of second trimester pathologic pregnancies. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 11 - Sayı: 1, 31–33. https://ajindex.com/articles/227580

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. El-Refaey H, Calder L, Wheatley DN, Templeton A. Cervical priming with prostaglandin El analogues; misoprostol and gameprost. Lancet 1994; 343:1207-9
  2. Ashok BW, Penney GC, Flett GMM, Templeton A. An effective regimen for early medical abortion; a report of 2000 consecutive cases. Hum Reprod 1998; 13:2962-5
  3. Ho PC, Ngai S W, Liu KL, Wong GCY, Lee SWH. Vaginal misoprostol compared with oral misoprostol in termination of second trimester pregnancy. Obstet Gynecol, 1997; 90:735-8
  4. Ngai SW, Au Yeung KC, Lao T, Ho PC. Oral misoprostol versus mifepristone for cervical dilatation before vacuum aspiration in first trimester nulliparous pregnancy: a double blind prospective randomized study. Br J Obstet Gynecol 1996; 103:1120-3
  5. Tang OS, Schureer H, Seyberth HW, Lee SWH, Ho PC. Pharmakinetics of different routes of administration of misoprostol. Human Reprod 2002; 17:332-6
  6. Garris RE, Kirkwood CF. Misoprostol: A prostaglandin El analogue. ClinPharm 1989; 8:627-44
  7. Zieman M, Fong SK, Benowitz NL, Bankster D, Darney PD. Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997; 90:88-92
  8. Danielsson KG, Marions L, Rodriguez A, Spur BW, Wong PYK, Bygdemon M. Comparison between oral and vaginal administration of misoprostol on uterine contractility. Obstet Gynecol 1999; 93:275-80
  9. Carlan Sİ, Bouldin S, O'Brien WF. Extemporaneous preparation of misoprostol gel for cervical ripening: A randomized trial. Obstet Gynecol 1997; 90:911-5
  10. Wing DA, Hamm D, Paul RH. A comparison of orally administered misoprostol with vaginally administered misoprostol for cervical ripening and labor induction. Obstet Gynecol 1999; 180:1155-60
  11. Wing DA, Paul RH. A comparison of different dosing regimens of vaginally administered misoprostol for preinduction cervical ripening and labor induction. Am J Obstet Gynecol 1996; 175:158-64 12. Hall R, Gardea MD, Harlass F. Oral versus vaginal misoprostol for labor induction. Obstet Gynecol 2002; 99:1044-8
  12. Taner CE, Güler A, Horasan F, Ege A, Alıhanoglu D. Termination of midtrimester pathologic pregnancies with intravaginal misoprostol. The 34th International Congress on Pathophysiology of Pregnancy, Balatonfiired, Lake Balaton, Hungary, 27-30 June 2002
  13. Blanchard K, Clark S, Wirikoff B, Gainess G, Kabani G, Shannon C. Misoprostol for women's health: A review. Obstet Gynecol 2002; 99:316-32
  14. Ramsey PS, Hogg BB, Savage KG, Winkler DD,0wen J. Cardiovascular effects of intravag