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Dergiler / GORM:Gynecology Obstetrics & Reproductive Medicine / 2020 / Cilt: 26 - Sayı: 3

The Association Between Abnormal Vaginal Flora and Cytological Evidence of HPV with Prematurity in High-Risk Pregnant Wom

Alana Dantas FREIRE
Ada Isa CUST DIO
Jos Queiroz FILHO
Jana na Crispim FREITAS
Ana Katherine GONÇALVES
Ricardo Ney COBUCCI
Sayfa
173–178
DOI
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CONCLUSIONS: We determined no association between abnormal cytology or altered vaginal flora in high-risk pregnancy in terms of overall preterm birth rate.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:OBJECTIVE: To evaluate the association between abnormal vaginal flora and cytological evidence of HPV with prematurity in high-risk pregnant women.
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Temel Bulgular & Veri:STUDY DESIGN: A prospective cohort study was designed with high-risk pregnant women who deliv-ered singletons between 20-42 gestational weeks between January to November 2018.
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Sonuç & Katkı:CONCLUSIONS: We determined no association between abnormal cytology or altered vaginal flora in high-risk pregnancy in terms of overall preterm birth rate.
🔬Tür:Araştırma Makalesi
📍Kapsam:2018 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

OBJECTIVE: To evaluate the association between abnormal vaginal flora and cytological evidence of HPV with prematurity in high-risk pregnant women. STUDY DESIGN: A prospective cohort study was designed with high-risk pregnant women who deliv-ered singletons between 20-42 gestational weeks between January to November 2018. Vaginal speci-mens were collected to obtain material from the upper lateral vaginal vault and cervix for direct micro-scopic examination of vaginal contents and preparation of Gram-stained and pap smear slides. Potential determinants of infection were assessed using the chi-square test. Poisson regression was used to de-termine the prevalence ratio and 95% confidence interval of the association between the vaginal flora and cytology with prematurity and a p<0.05 was considered as statistical significance. RESULTS: A total of 68 pap smear and high vaginal swab samples were collected from high-risk preg-nant women with a mean age of 30.3 years. There were 26 (38.2%) cases of abnormal vaginal flora and 6 (8.8%) of HPV-induced cytological abnormalities. The preterm delivery rate was comparable between women with normal and abnormal vaginal flora (11.9% vs. 11.5%, prevalence ratio 1.0 [95% confidence interval: 0.8-1.2], aPR 1.0 [95% confidence interval: 0.8-1.2]) and between women with and without ab-normal cytology (16.7% vs. 11.3%, prevalence ratio 0.9 [95% confidence interval: 0.6-1.4], aPR 0.9 [95% confidence interval: 0.6-1.4]). CONCLUSIONS: We determined no association between abnormal cytology or altered vaginal flora in high-risk pregnancy in terms of overall preterm birth rate.

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Bu Makaleye Atıf Yap

FREIRE, A. D., DIO, A. I. C., FILHO, J. Q., FREITAS, J. N. C., GONÇALVES, A. K., COBUCCI, R. N. (2020). The Association Between Abnormal Vaginal Flora and Cytological Evidence of HPV with Prematurity in High-Risk Pregnant Wom. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 26 - Sayı: 3, 173–178. https://ajindex.com/articles/226970

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Kaynakça (11)

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