KaydedilenlerDerginizi ekleyin

Dergiler / Acta Orthopaedica et Traumatologica Turcica / 2015 / Cilt: 49 - Sayı: 3

Effects of intra-articular levobupivacaine, fentanyllevobupivacaine and tramadol-levobupivacaine for postoperative pain in arthroscopic knee surgery

Pınar SAYIN
Hale DOBRUCALI
Hacer Şebnem TÜRK
Tolga TOTOZ
Canan Tülay IŞIL
Ayşe HANCI
Sayfa
267–273
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: The results indicated that levobupivacaine combined with either fentanyl or tramadol decreased rescue analgesic requirements when compared to levobupivacaine alone.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: The aim of this study was to compare the postoperative analgesic efficacy of intra-articularly injected levobupivacaine, levobupivacaine-fentanyl, and levobupivacaine-tramadol combinations.
📊
Temel Bulgular & Veri:Methods: Eighty patients scheduled for elective knee arthroscopy were divided randomly into 4 groups of 20 patients each.
💡
Sonuç & Katkı:Conclusion: The results indicated that levobupivacaine combined with either fentanyl or tramadol decreased rescue analgesic requirements when compared to levobupivacaine alone.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: The aim of this study was to compare the postoperative analgesic efficacy of intra-articularly injected levobupivacaine, levobupivacaine-fentanyl, and levobupivacaine-tramadol combinations. Methods: Eighty patients scheduled for elective knee arthroscopy were divided randomly into 4 groups of 20 patients each. Group 1 (the control group) received intra-articular saline, Group 2 received levobupivacaine 2.5 mg/ml, Group 3 received levobupivacaine 2.5 mg/ml + tramadol 50 mg, and Group 4 received levobupivacaine 2.5 mg/ml + fentanyl l50 mcg. All patients were operated on under general anesthesia, and a total of 20 ml study solution was injected: 7 ml subcutaneously before surgery and 13 ml intra-articularly upon completion of surgery. For postoperative, pain visual analogue scale (VAS) was assessed at the 1st, 2nd, 4th, 8th, 12th, and 24th hours postoperatively. Patients with a VAS score over 5 received diclofenac sodium, and the need for rescue analgesics was recorded. Results: At the 1st, 2nd, 4th, 8th, 12th, and 24th postoperative hours, Group 3 and Group 4 had statistically significant lower VAS scores of pain (p<0.01). Postoperative rescue analgesic requirements were different among the groups. The postoperative 1st hour analgesic requirement was statistically significantly lower in Group 3 and Group 4 when compared to the other groups (p<0.01). At the postoperative 2nd and 4th hours, analgesic requirements were statistically significantly lower in Group 3 than in the other groups (p<0.01). Analgesic requirements were statistically significantly lower in Group 3 and Group 4 than in the other groups (p<0.01). Analgesic requirements at the 12th and 24th postoperative hours did not show any statistically significant difference (p>0.05). Conclusion: The results indicated that levobupivacaine combined with either fentanyl or tramadol decreased rescue analgesic requirements when compared to levobupivacaine alone.

🔖

Bu Makaleye Atıf Yap

SAYIN, P., DOBRUCALI, H., TÜRK, H. Ş., TOTOZ, T., IŞIL, C. T., HANCI, A. (2015). Effects of intra-articular levobupivacaine, fentanyllevobupivacaine and tramadol-levobupivacaine for postoperative pain in arthroscopic knee surgery. Acta Orthopaedica et Traumatologica Turcica, Cilt: 49 - Sayı: 3, 267–273. https://ajindex.com/articles/215438

Kaynakça (12)

  1. Eren M, Koltka K, Köknel Talu G, Aşık M, Özyalçın S. Comparison of analgesic activity of intraarticular lornoxicam, bupivacaine and saline after knee arthroscopy. Agri 2008;20:17-22
  2. De Andrés J, Valía JC, Barrera L, Colomina R. Intraarticular analgesia after arthroscopic knee surgery: comparison of three different regimens. Eur J Anaesthesiol 1998;15:10–5
  3. In Morgan GE, Mikhail MS, Murray MJ. Lokal anestezikler (Local anesthetics). Tulunay M, Cuhruk H, ed. Klinik Anesteziyoloji (Clinical Anesthesiology), 3. Türkçe Baskı, Ankara: Güneş Kitabevi; 2004. s. 233–52
  4. Gristwood RW. Cardiac and CNS toxicity of levobupivacaine: strengths of evidence for advantage over bupivacaine. Drug Saf 2002;25:153–63
  5. Geutjens G, Hambidge JE. Analgesic effects of intraarticular bupivacaine after day-case arthroscopy. Arthroscopy 1994;10:299–300
  6. Brill S, Plaza M. Non-narcotic adjuvants may improve the duration and quality of analgesia after knee arthroscopy: a brief review. Can J Anaesth 2004;51:975–8
  7. Tverskoy M, Braslavsky A, Mazor A, Ferman R, Kissin I. The peripheral effect of fentanyl on postoperative pain. Anesth Analg 1998;87:1121–4
  8. Jawish D, Antakly MC, Dagher F, Nasser E, Geahchan N. Intra-articular analgesia after arthroscopy of the knee. [Article in French] Cah Anesthesiol 1996;44:415–7
  9. Mandal P, Saudagar AH. Intra-articular fentanyl for analgesia following artroscopic knee surgery. Indian Journal of Anesthesia 2002;46:107–10 10. Varkel V, Volpin G, Ben-David B, Said R, Grimberg B, Simon K, et al. Intraarticular fentanyl compared with morphine for pain relief following arthroscopic knee surgery. Can J Anaesth 1999;46:867–71
  10. Beyzadeoglu T, Yilmaz C, Bekler H, Gokce A, Sayin MM. Intraarticular tramadol plus pericapsular incisional bupivacaine provides better analgesia than intraarticular plus pericapsular incisional bupivacaine after outpatient arthroscopic partial meniscectomy. Knee Surg Sports Traumatol Arthrosc 2007;15:564–8
  11. Zeidan A, Kassem R, Nahleh N, Maaliki H, El-Khatib M, Struys MM, et al. Intraarticular tramadol-bupivacaine combination prolongs the duration of postoperative analgesia after outpatient arthroscopic knee surgery. Anesth Analg 2008;107:292–9
  12. Hosseini H, Abrisham SM, Jomeh H, Kermani-Alghoraishi M, Ghahramani R, Mozayan MR. The comparison of intraarticular morphine-bupivacaine and tramadol-bupivacaine in postoperative analgesia after arthroscopic anterior cruciate ligament reconstruction. Knee Surg Spor