Dergiler / Bezmiâlem Science / 2021 / Cilt: 9 - Sayı: 1

Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation

Hematopoetik Kök Hücre Nakli Yapılmış Bir Talasemi Majör Hastasında COVID- 19’un Klinik Seyri

Sayfa
91–93
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this case report, we wanted to point out that the course of the COVID-19 is unexpectedly mild in such a patient with thalassemia major.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease.
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Temel Bulgular & Veri:The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high fever and weakness.
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Sonuç & Katkı:In this case report, we wanted to point out that the course of the COVID-19 is unexpectedly mild in such a patient with thalassemia major.
🔬Tür:Araştırma Makalesi
📍Kapsam:2013 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

We herein reported the course of Coronavirus diasease-19 (COVID-19) in a 21-year-old patient with thalassemia majo rdisease. The patient who underwent haematopoietic stem cell transplantation in 2013 and developed alloimmunization, presented with high fever and weakness. His parents have been recently diagnosed with COVID-19. COVID-19 diagnosis was confirmed by real time-polymerase chain reaction (RT-PCR) method in the nasopharyngeal swab sample of the patient while his thorax computed tomography was not found in favor of pneumonia. The patient was treated with hydroxychloroquine 2x200mg and Favipravir 3x600mg. The temperature fell with in three days. The clinical condition of the patient improved rapidly. On the 20th day, he did not have any symptom with a recovery of anemia and lymphopenia, but the RT-PCR result was stil positive. In this case report, we wanted to point out that the course of the COVID-19 is unexpectedly mild in such a patient with thalassemia major.

Abstract

Talasemi major hastalığı olan 21 yaşındaki bir hastada Koronavirüs hastalığı-19’un (COVİD-19) klinik seyri sunulmuştur. 2013 yılında hematopoetik kök hücre nakli yapılmış ve alloimmunizasyon gelişmiş hasta, yüksek ateş ve halsizlik şikayeti ile başvurdu. Yakın zamanda anne ve babası COVİD-19 tanısı almıştı. Toraks tomografisinde pnömoni lehine bulgu saptanmayan hastanın COVİD-19 tanısı nazofarengeal sürüntü örneğinde gerçek zamanlı polimeraz zincir reaksiyonu (RT-PCR) yöntemiyle doğrulandı. Hastaya hidroksiklorokin 2x200 mg ve favipravir 3x600 mg tedavisi başlandı. Ateşi üç gün sonra düştü. Hastanın klinik durumu hızla iyileşti. Anemi ve lenfopenisi düzelen hastanın, tedavinin 20. gününde herhangi bir semptomu yoktu. Ancak RT-PCR sonucu hala pozitif idi. Bu olgu sunumuyla talasemi majörü olan bir hastada, COVID-19’un beklenmedik biçimde hafif seyrettiğine dikkati çekmek istedik.

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Bu Makaleye Atıf Yap

HAMİDİ, A. A., ULU, Y., AKTAŞ, H. (2021). Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation. Bezmiâlem Science, Cilt: 9 - Sayı: 1, 91–93. https://ajindex.com/articles/212972

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